Clavulin

The recommended adult dose of amoxicillin - clavulanic acid depends on the infection being treated. The usual recommended adult doses include 500 mg every 8 or 12 hours or 875 mg every 12 hours.

The children's dose of amoxicillin - clavulanic acid is based on body weight, as prescribed by the doctor. Depending on the infection being treated, the dose will range between 20 mg and 45 mg per kilogram of body weight per day, taken in divided doses.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

The medication may be taken with or without food, but taking it with food may reduce side effects such as upset stomach, nausea, Diarrhea, and abdominal cramps. Amoxicillin - clavulanic acid is usually taken for a period of 7 to 10 days. In some cases, it may be necessary to take Clavulin for a longer period.

If using the suspension form, use an oral syringe to measure each dose to get a more accurate measurement than household teaspoons.

It is very important to take Clavulin exactly as prescribed by the doctor for the full duration of treatment, even though you may feel better before the medication is finished. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store the tablets at room temperature, protect them from light and moisture, and keep them out of the reach of children.

Store the suspension in the refrigerator and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Suspension

Clavulin-125F
Each 5 mL of reconstituted suspension contains 125 mg of amoxicillin as the trihydrate and 31.25 mg of clavulanic acid as the potassium salt (in a ratio of 4:1). Nonmedicinal ingredients: aspartame, colloidal silica, flavours (golden syrup dry, orange dry 1, orange dry 2, raspberry dry), hydroxypropyl methylcellulose, silicon dioxide, succinic acid, and xanthan gum.

Clavulin-200
Each 5 mL of reconstituted suspension contains 200 mg of amoxicillin as the trihydrate and 28.5 mg of clavulanic acid as the potassium salt (in a ratio of 7:1). Nonmedicinal ingredients: aspartame, colloidal silica, flavours (golden syrup dry, orange dry 1, orange dry 2, raspberry dry), hydroxypropyl methylcellulose, silicon dioxide, succinic acid, and xanthan gum.

Clavulin-250F
Each 5 mL of reconstituted suspension contains 250 mg of amoxicillin as the trihydrate and 62.5 mg of clavulanic acid as the potassium salt (in a ratio of 4:1). Nonmedicinal ingredients: aspartame, colloidal silica, flavours (golden syrup dry, orange dry 1, orange dry 2, raspberry dry), hydroxypropyl methylcellulose, silicon dioxide, succinic acid, and xanthan gum.

Clavulin-400
Each 5 mL of reconstituted suspension contains 400 mg of amoxicillin as the trihydrate and 57 mg of clavulanic acid as the potassium salt (in a ratio of 7:1). Nonmedicinal ingredients: aspartame, colloidal silica, flavours (golden syrup dry, orange dry 1, orange dry 2, raspberry dry), hydroxypropyl methylcellulose, silicon dioxide, succinic acid, and xanthan gum.

Tablets

Clavulin-500F
Each scored, white, oval, film-coated tablet, marked with "AC" on one side, contains 500 mg of amoxicillin as the trihydrate and 125 mg of clavulanic acid as the potassium salt (in a ratio of 4:1). Nonmedicinal ingredients: colloidal silica, dimethicone 500, hydroxypropyl methylcellulose (methocel E5), hydroxypropyl methylcellulose (methocel E15), magnesium stearate, microcrystalline cellulose, polyethylene glycol 4000, polyethylene glycol 6000, sodium starch glycolate, and titanium dioxide.

Clavulin-875
Each scored, white, capsule-shaped tablet, marked with "AC" on both sides, contains 875 mg of amoxicillin as the trihydrate and 125 mg of clavulanic acid as the potassium salt (in a ratio of 7:1). Nonmedicinal ingredients: colloidal silica, dimethicone 500, hydroxypropyl methylcellulose (methocel E5), hydroxypropyl methylcellulose (methocel E15), magnesium stearate, microcrystalline cellulose, polyethylene glycol 4000, polyethylene glycol 6000, sodium starch glycolate, and titanium dioxide.

Do not take Clavulin if you:

• are allergic to amoxicillin, penicillin, cephalosporins (e.g., Cephalexin, Ceftriaxone), clavulanic acid, or any ingredients of the medication
• have had jaundice or liver problems with previous use of Clavulin
• have or are suspected to have mononucleosis

There may be an interaction between amoxicillin - clavulanic acid and any of the following:

• Allopurinol
• BCG
• birth control pills
• Cholera vaccine
• Methotrexate
• mycophenolate
• sodium picosulfate
• tetracyclines (e.g., Tetracycline, Minocycline, doxycycline)
• typhoid vaccine
• Warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Clavulin. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Clavulin.

Allergy: Amoxicillin, one of the ingredients in Clavulin, is a penicillin. If you have previously had an allergic reaction to antibiotics such as penicillin or cephalosporins (e.g., cephalexin, ceftriaxone), you should not take Clavulin. Before you take amoxicillin - clavulanic acid, inform your doctor about any previous adverse reactions you have had to medications, especially cephalosporins and penicillins.

Get immediate medical attention if you experience symptoms of a severe allergic reaction (e.g., hives; swelling of the face, tongue, or throat; trouble breathing).

Antibiotic-associated colitis: Clavulin, like other antibiotics, may cause a potentially dangerous condition called antibiotic-associated, or pseudomembranous, colitis. Symptoms include severe, watery diarrhea that may be bloody. If you notice these symptoms, stop taking amoxicillin - clavulanic acid and contact your doctor as soon as possible.

Aspartame: The suspension forms of Clavulin contain aspartame. If you have phenylketonuria, discuss with your doctor how Clavulin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Clavulin, and whether any special monitoring is needed.

Bacterial resistance: Misuse of an antibiotic such as amoxicillin - clavulanic acid may lead to the growth of resistant bacteria that will not be killed by the antibiotic. If this happens, the antibiotic may not work for you in the future. Although you may begin to feel better early in your course of treatment with Clavulin, you need to take the full course exactly as directed to finish ridding your body of the infection and to prevent resistant bacteria from taking hold. Do not take amoxicillin - clavulanic acid or other antibiotics to treat a viral infection such as The Common Cold; antibiotics do not kill viruses, and using them to treat viral infections can lead to the growth of resistant bacteria.

Birth control: Clavulin may decrease the effectiveness of birth control pills. Some doctors recommend adding another method of birth control for the rest of the cycle when amoxicillin-clavulanate is taken.

Kidney function: Clavulin is removed from the body mostly by the kidneys. If you have Kidney Disease or reduced kidney function, Clavulin may build up in your body and cause unwanted effects.

If you have kidney problems, discuss with your doctor how Clavulin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Clavulin, and whether any special monitoring is needed.

Liver function: If you have liver disease or reduced liver function, discuss with your doctor how Clavulin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Clavulin, and whether any special monitoring is needed.

Clavulanic acid may cause a decrease in liver function. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Mononucleosis: When amoxicillin - clavulanic acid is used by a person who has mononucleosis, a widespread rash may occur. If you have or suspect you have mononucleosis, discuss with your doctor how Clavulin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Clavulin, and whether any special monitoring is needed.

Clavulin should not be used by anyone who has or is suspected to have mononucleosis.

Overgrowth of organisms (super-infection): Prolonged or repeated use of this antibiotic may allow normal fungus or certain types of bacteria not killed by the antibiotic to overgrow, causing unwanted infections such as yeast infections. Contact your doctor if you notice white patches in the mouth (thrush), abnormal vaginal discharge, or itching.

Pregnancy: Clavulin should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Clavulin, contact your doctor immediately.

Breast-feeding: Amoxicillin passes into breast milk. It is not known if clavulanic acid passes into breast milk. If you are a breast-feeding mother and are taking Clavulin, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.