Dexilant

For the treatment of erosive esophagitis, the usual dose of Dexilant (Dexlansoprazole) is 60 mg once daily for up to 8 weeks.

To maintain the healing of erosive esophagitis, the usual dose is 30 mg once daily for up to 6 months. In cases where the erosive esophagitis was considered moderate to severe, the dose may be increased to 60 mg taken once daily.

For heartburn associated with GERD, the usually dose is 30 mg once daily for 4 weeks.

Adolescents between the ages of 12 and 17 may use the same doses as adults for treatment of these conditions. To maintain the healing of erosive esophagitis, the usual length of treatment for adolescents is up to 4 months.

Dexilant (Dexlansoprazole) can be taken with or without food. It should be swallowed whole with lots of water. Alternatively, the contents of the capsule can be sprinkled on one tablespoon of applesauce and swallowed immediately. The granules should not be chewed.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Dexilant (Dexlansoprazole) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Dexilant (Dexlansoprazole) at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

In addition to its desired action, this medication may cause some adverse effects, notably: it may cause diarrhea; it may cause stomach ache; it may cause gas and bloating. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.

30 mg
Each opaque, blue and gray capsule with "TAP" and "30" imprinted on the capsule contains 30 mg of Dexilant (Dexlansoprazole). Nonmedicinal ingredients: colloidal silicon dioxide, hydroxypropyl cellulose, hypromellose 2910, low-substituted hydroxypropyl cellulose, magnesium carbonate, methacrylic acid copolymer, polyethylene glycol 8000, polysorbate 80, sucrose, sugar spheres, talc, titanium dioxide, and triethyl citrate; capsule shell: black ferric oxide, carrageenan, FD&C Blue No. 2 Aluminum Lake, hypromellose, potassium chloride, and titanium dioxide.

60 mg
Each opaque, blue capsule with "TAP" and "60" imprinted on the capsule contains 60 mg of Dexilant (Dexlansoprazole). Nonmedicinal ingredients: colloidal silicon dioxide, hydroxypropyl cellulose, hypromellose 2910, low-substituted hydroxypropyl cellulose, magnesium carbonate, methacrylic acid copolymer, polyethylene glycol 8000, polysorbate 80, sucrose, sugar spheres, talc, titanium dioxide, and triethyl citrate; capsule shell: carrageenan, FD&C Blue No. 2 Aluminum Lake, hypromellose, potassium chloride, and titanium dioxide.

Do not take Dexilant (Dexlansoprazole) if you:

• are allergic to Dexilant (Dexlansoprazole) or to any of the ingredients of the medication
• are taking the medication rilpivirine

There may be an interaction between Dexilant (Dexlansoprazole) and any of the following:

• alcohol
• amphetamines (e.g., Dextroamphetamine, Lisdexamfetamine)
• "azole" antifungals (e.g., itraconazole, ketoconazole, Voriconazole)
• bisphosphonates (e.g., Alendronate, etidronate)
• Capecitabine
• cefuroxime
• Clopidogrel
• cysteamine
• dabigatran
• delavirdine
• dexmethylphenidate
• doxycycline
• HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
• iron supplements
• ledipasvir
• Mesalamine
• Methylphenidate
• methotrexate
• multivitamins with iron, folate
• mycophenolate
• raltegravir
• rilpivirine
• Riociguat
• Tacrolimus
• tyrosine kinase inhibitors (e.g., Crizotinib, Dasatinib, imatinib, Nilotinib, Pazopanib)
• velpatasvir
• Warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Dexilant (Dexlansoprazole). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Dexilant (Dexlansoprazole).

Diarrhea: When gastric acid is decreased, the number of bacteria normally in the digestive system increases. Occasionally, this can cause serious infection in the digestive tract. If you experience watery, foul-smelling bowel movements after starting to take Dexilant (Dexlansoprazole), contact your doctor as soon as possible.

Fractures: Long-term use of proton-pump inhibitors has been associated with an increased risk for osteoporosis-related fracture of the hip, wrist, or spine, particularly for people who take Dexilant (Dexlansoprazole) for a year or longer. If you have Osteoporosis or have risk factors for developing osteoporosis, discuss with your doctor how Dexilant (Dexlansoprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dexilant (Dexlansoprazole), and whether any special monitoring is needed.

Liver problems: People with liver problems should discuss with their doctor how Dexilant (Dexlansoprazole) may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Dexilant (Dexlansoprazole), and whether any special monitoring is needed.

Magnesium levels: In rare instances, Dexilant (Dexlansoprazole) may cause low magnesium levels in people who take Dexilant (Dexlansoprazole) for a prolonged period of time. Low magnesium may occur after at least 3 months, but usually after a year of treatment. If you have low magnesium levels in your blood, you should discuss with your doctor how Dexilant (Dexlansoprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dexilant (Dexlansoprazole), and whether any special monitoring is needed.

Methotrexate interaction: Dexilant (Dexlansoprazole), like other medications in this group, may interact with methotrexate when the two medications are used at the same time. This combination may lead to higher than expected amounts of methotrexate in the body and can cause serious side effects, including kidney damage, irregular heartbeat, Anemia, or infection. If you take Dexilant (Dexlansoprazole) and are also going to receive a dose of methotrexate, discuss with your doctor how Dexilant (Dexlansoprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dexilant (Dexlansoprazole), and whether any special monitoring is needed.

Other stomach problems: Even if you experience improvement in acid-related symptoms, it is still possible to have serious underlying stomach problems such as stomach cancer. Talk to your doctor if you have other symptoms of stomach problems such as loss of appetite, nausea, vomiting, a bloated feeling after eating, changes in bowel habits, or unexplained weight loss or fatigue.

Vitamin B12: Long-term use of Dexilant (Dexlansoprazole) may lead to vitamin B12 deficiency. If you are a vegetarian or have low vitamin B12 levels, discuss with your doctor whether any special monitoring is required.

Pregnancy: Dexilant (Dexlansoprazole) should not be taken during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Dexilant (Dexlansoprazole), contact your doctor immediately.

Breast-feeding: It is not known if Dexilant (Dexlansoprazole) passes into breast milk. If you are a breast-feeding mother and are taking Dexilant (Dexlansoprazole), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Dexilant (Dexlansoprazole) have not been established for children under 12 years old.

This medication is typically used only once a day. However, your pharmacist may have suggested a different schedule that is more appropriate for you. Take it regularly and continuously to maintain its beneficial effects. If desired, the capsule can be opened and the contents sprinkled on soft food. The small granules, however, must NOT be chewed. Avoid using or consuming substances that may irritate your stomach, such as: Cigarettes Alcohol and alcohol-containing products Coffee, tea and chocolate Acidic or spicy food Fried foods If you forget a dose, take it as soon as you remember -- unless it is almost time for your next dose. In that case, skip the missed dose. Do not double the next dose to catch up. This medication may be taken with or without food.