
Dicyclomine
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Dicyclomine - clinical reference
A licensed healthcare practitioner can help you understand what applies to your specific situation.
The usual adult dose of dicyclomine is 10 to 20 mg taken three to four times a day depending on your response.
The dose is usually increased after the first week of therapy up to a maximum of 40 mg four times a day. If you do not get any relief of your signs and symptoms with Dicyclomine after 2 weeks or cannot tolerate more than 80 mg per day, your doctor may choose to stop Dicyclomine.
The usual dose for children between 2 and 12 years of age is 10 mg three to four times daily.
Infants between 6 months and 2 years of age should receive 5 to 10 mg taken 3 to 4 times daily to be given 15 minutes before feeding. The syrup form of dicyclomine should be mixed with an equal volume of water before taking it.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Use an oral syringe to measure each dose of the liquid, as it gives a more accurate measurement than household teaspoons.
It is important to take Dicyclomine exactly as prescribed by your doctor.
If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Dicyclomine at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
In addition to its desired action, this medication may cause some adverse effects, notably: it may cause blurred vision and dryness of the mouth; it may cause drowsiness or dizziness - use caution when getting up from a lying or sitting position and use caution if driving; it may cause a general feeling of weakness; it may cause nausea or, rarely, vomiting. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.
Capsule
Dicyclomine is available as a 10 mg capsule.
Injection
Dicyclomine is available as a 10 mg/mL injectable solution.
Do not take dicyclomine if you:
- are allergic to dicyclomine or any ingredients of the medication
- have a blockage of the urinary tract
- have a blockage of the gastrointestinal tract
- have paralytic ileus (decreased movement of material through the digestive system) or intestinal atony (paralysis of the intestines)
- have severe Ulcerative Colitis
- have Myasthenia Gravis
- have esophagus irritation caused by acid reflux from the stomach
- have Glaucoma (increased pressure in the eye)
- have constantly changing blood pressure and heart function due to bleeding
- are currently breast feeding
Do not give Dicyclomine to infants under 6 months of age.
There may be an interaction between dicyclomine and any of the following:
- anti-arrhythmic medications (e.g., quinidine)
- antihistamines (e.g., Chlorpheniramine, Diphenhydramine, Hydroxyzine)
- antipsychotics (e.g., Chlorpromazine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
- atropine
- Benztropine
- Cyclobenzaprine
- Dimenhydrinate
- Donepezil
- dronabinol
- Galantamine
- ipratropium
- monoamine oxidase inhibitors (M.O.S. e.g., Moclobemide, Phenelzine, Tranylcypromine)
- Nabilone
- narcotic opioids (e.g., Codeine, Fentanyl, Meperidine, Morphine)
- orphenadrine
- Oxybutynin
- phenothiazines (e.g., Fluphenazine, Perphenazine)
- potassium chloride
- procyclidine
- Rivastigmine
- scopolamine
- tricyclic antidepressants (e.g., Amitriptyline, Desipramine, Trimipramine)
- Trihexyphenidyl
- tiotropium
- Topiramate
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Dicyclomine. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Dicyclomine.
Blood pressure: Dicyclomine may cause Low Blood Pressure resulting in sudden dizziness when you stand up rapidly. Take care when first using Dicyclomine.
Drowsiness/reduced alertness: Dicyclomine may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid these and other hazardous tasks until you have determined how Dicyclomine affects you.
Glaucoma: Dicyclomine may make the symptoms of glaucoma, such as blurred vision, to become more noticeable. If you have glaucoma, discuss with your doctor how Dicyclomine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dicyclomine, and whether any special monitoring is needed.
Heart disease: Some medications used to treat irregular heartbeat, Congestive Heart Failure, and high blood pressure can cause an increase in the effects of dicyclomine. If you are taking medications for any of these conditions, or are at risk for developing any of these conditions, discuss with your doctor how Dicyclomine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dicyclomine, and whether any special monitoring is needed.
Kidney and liver condition: The removal of Dicyclomine from your body may be affected by liver and kidney disorders. If you have existing liver or kidney conditions, discuss with your doctor how Dicyclomine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dicyclomine, and whether any special monitoring is needed.
Prostate enlargement: Dicyclomine may cause difficulty staring to urinate, making symptoms of prostate hypertrophy (enlargement) worse. If you have prostatic hypertrophy, discuss with your doctor how Dicyclomine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dicyclomine, and whether any special monitoring is needed.
Thyroid disease: If you have an overactive thyroid gland, discuss with your doctor how Dicyclomine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dicyclomine, and whether any special monitoring is needed.
Pregnancy: Dicyclomine should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Dicyclomine, contact your doctor immediately.
Breast-feeding: Dicyclomine passes into breast milk. If you are a breast-feeding mother and are taking dicyclomine, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Dicyclomine have not been established for children less than 6 months of age and should be avoided in this age group.
Seniors: Seniors may be more likely to experience severe side effects of dicyclomine. It may be necessary to use lower doses than those reported above.
This medication is typically used 4 times a day. However, your pharmacist may have suggested a different schedule that is more appropriate for you. Generally, it is used only as needed. Important: Follow the instructions on the label. Do not use more of this product, or more often, than prescribed. This medication should be taken 30 minutes before a meal.









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