20mcg/ml

The dose varies according to age and dosing schedule. Hepatitis B vaccine should be used only by or under the supervision of a doctor. A qualified health professional will inject the hepatitis B vaccine.

The dose of hepatitis B vaccine is injected into a muscle (preferably the upper, outer arm for adults and the thigh for infants and children) with 3 doses that are at least 1 month apart. A two-dose regimen is available for adolescents (11 to 15 years of age) where the second dose is given 4 to 6 months after the first.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. Other dosing schedules are sometimes used. It is very important to keep doctor appointments so that 20mcg/mL (Hepatitis-b-vaccine) may be used according to recommended schedules. Add all vaccines you receive to your immunization record.

This vaccine is stored in the refrigerator and protected from light until it is used. It should be kept out of the reach of children, and it must not be allowed to freeze or it will have to be discarded.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

In addition to its desired action, this medication may cause some adverse effects, notably: it may cause headaches; it may cause indigestion; it may cause dizziness - use caution when getting up from a lying or sitting position and use caution if driving; it may cause unusual tiredness; it could make you more prone to respiratory infections; it may cause redness and swelling at the injection site. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.

Engerix®-B
Each 1 mL adult dose contains 20 µg of hepatitis B surface antigen adsorbed onto 0.5 mg of aluminum hydroxide. Nonmedicinal ingredients: aluminum hydroxide. The vaccine is a slightly opaque, white, sterile suspension. A slow settling of the white aluminum hydroxide may occur during storage leaving a clear, colourless, supernatant liquid. Thimerosal-free

Engerix®-B Pediatric Dose
Each 0.5 mL pediatric dose contains 10 µg of hepatitis B surface antigen adsorbed onto 0.25 mg of aluminum hydroxide. Nonmedicinal ingredients: aluminum hydroxide. The vaccine is a slightly opaque, white, sterile suspension. A slow settling of the white aluminum hydroxide may occur during storage leaving a clear, colourless, supernatant liquid. Thimerosal-free.

Hepatitis B vaccine should not be used by anyone who is allergic to hepatitis B vaccine or to any of the ingredients of the medication.

There may be an interaction between hepatitis B vaccine and any of the following:

• Acetaminophen
• Abatacept
• Azathioprine
• Baricitinib
• Belimumab
• cancer medications (e.g., Carboplatin, Cyclophosphamide, Doxorubicin, Ifosfamide, Vincristine)
• corticosteroids (e.g., budesonide, Dexamethasone, Hydrocortisone, fluticasone, Prednisone)
• Cyclosporine
• eculizumab
• Etanercept
• Fingolimod
• Golimumab
• Hydroxyurea
• Infliximab
• Ixekizumab
• Leflunomide
• mycophenolate
• Rituximab
• Romidepsin
• Secukinumab
• siltuximab
• Sirolimus
• Tacrolimus
• teriflumomide
• Tocilizumab
• Tofacitinib
• Vedolizumab
• vaccines
• Warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with 20mcg/mL (Hepatitis-b-vaccine). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you receive 20mcg/mL (Hepatitis-b-vaccine), be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use 20mcg/mL (Hepatitis-b-vaccine).

Hemodialysis: People undergoing hemodialysis have a reduced immune response to the hepatitis B vaccine. Additional and higher doses of the vaccine may be required. Discuss any concerns you have with your doctor.

Immune deficiency or suppression: People with immunodeficiency or those receiving immunosuppressive therapy (e.g., some medications used for the treatment of cancer or for transplant recipients) may require higher doses and may not respond as well as healthy individuals.

Infection: The vaccine should be delayed for people with serious infections, unless in the opinion of the doctor there is a greater risk associated with not giving the vaccine.

Vaccine protection: As with any vaccine, this vaccine may not protect 100% of people who receive it. (NOTE: Hepatitis B vaccine may not prevent hepatitis in people who were infected with the virus prior to receiving the vaccine.)

Pregnancy: 20mcg/mL (Hepatitis-b-vaccine) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while receiving 20mcg/mL (Hepatitis-b-vaccine), contact your doctor immediately.

Breast-feeding: It is not known if the vaccine passes into breast milk. If you are a breast-feeding mother and are receiving this vaccine, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: This vaccine can be used in babies and children.

This medication must be administered by a health professional. Because complete vaccination requires several doses of this product to be given at specific times, it is important to keep your scheduled appointments.