Lupron 14 Days Kit

The recommended dose of Lupron 14 Days Kit (Leuprolide) depends on the condition being treated and the frequency of injection that is most convenient for your condition.

Lupron 14 Days Kit (Leuprolide) is available as a daily injection (under the skin) or as a long-acting injection (into the muscle every 1, 3, or 4 months).

If you are giving yourself or your child daily injections, it is very important to follow the directions as printed on the package insert.

Be sure to check the solution for discolouration and particle matter before each use. Presterilized disposable syringes are supplied and the usual sites of injection are indicated in the package insert. To avoid damage to your skin and tissues, it is important to change the injection site on your body from time to time as recommended by your doctor.

The long-acting form of Lupron 14 Days Kit (Leuprolide) (depot) is injected into your muscle by your doctor at the appropriate intervals. It is very important to receive Lupron 14 Days Kit (Leuprolide) at the correct times. If you miss your appointment for an injection, make a new one as soon as possible.

It is important that Lupron 14 Days Kit (Leuprolide) be administered exactly as prescribed by your doctor. If you are using the daily injections and miss a dose, administer it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Many things can affect the dose and schedule of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose or schedule different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

Check the packaging instructions to find out whether to store Lupron 14 Days Kit (Leuprolide) in the refrigerator or at room temperature, as different brands have different requirements. Once mixed, the suspension should be used immediately or discarded. Protect from freezing and keep out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

5 mg vial
Each mL contains 5 mg of Lupron 14 Days Kit (Leuprolide) acetate. Nonmedicinal ingredients: benzyl alcohol, sodium chloride, and sterile water for injection USP.

Do not use Lupron 14 Days Kit (Leuprolide) if you:

• are allergic to Lupron 14 Days Kit (Leuprolide) acetate or any ingredients of the medication
• are breast-feeding
• are or may become pregnant
• have undiagnosed abnormal vaginal bleeding

There may be an interaction between Lupron 14 Days Kit (Leuprolide) and any of the following:

• antiarrhythmics (e.g., Amiodarone, Disopyramide, Dronedarone, procainamide, Propafenone, quinidine)
• antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
• "azole" antifungals (e.g., itraconazole, ketoconazole, Voriconazole)
• beta 2-agonists (e.g., formoterol, Indacaterol, olodaterol, salbutamol, salmeterol)
• diabetes medications (e.g., chlorpropamide, Glyburide, insulin, Metformin, Rosiglitazone)
• macrolide antibiotics (e.g., clarithromycin, erythromycin)
• Methadone
• protein kinase inhibitors (e.g., Dasatinib, imatinib, Nilotinib)
• quinine
• selective serotonin reuptake inhibitors (SSRIs, e.g., Citalopram, Fluoxetine, Paroxetine, Sertraline)
• Sotalol
• Trazodone
• tricyclic antidepressants (e.g., Amitriptyline, Clomipramine, Desipramine, Trimipramine)

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Lupron 14 Days Kit (Leuprolide). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Lupron 14 Days Kit (Leuprolide).

Depression: Sex hormones influence mood swings and symptoms of depression. If you have depression or a history of depression, discuss with your doctor how Lupron 14 Days Kit (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lupron 14 Days Kit (Leuprolide), and whether any special monitoring is needed.

Diabetes: Lupron 14 Days Kit (Leuprolide) may cause a loss of blood glucose control, and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Lupron 14 Days Kit (Leuprolide). If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Lupron 14 Days Kit (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lupron 14 Days Kit (Leuprolide), and whether any special monitoring is needed.

Liver function: In rare cases, Lupron 14 Days Kit (Leuprolide) has been reported to cause liver failure or inflammation of the liver. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Men and heart-related conditions: There may be an increased risk of heart-related events (e.g., heart attacks, Stroke, heart-related death) for men being treated for prostate cancer with GnRH medications. Before you start treatment, tell your doctor if you have diabetes, heart disease, had a previous Heart Attack or stroke, or have cardiovascular risk factors (e.g., high blood pressure, smoking, or cholesterol). If you have any of these conditions, discuss with your doctor how Lupron 14 Days Kit (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lupron 14 Days Kit (Leuprolide), and whether any special monitoring is needed.

Osteoporosis: Over time, Lupron 14 Days Kit (Leuprolide) can cause the bones to lose thickness. People who are at risk for osteoporosis, such as those with a family history of osteoporosis, long-term alcohol or tobacco use, or who are taking other medications that tend to thin bones, such as seizure medications or long-term use of corticosteroids, are more likely to experience this loss of bone. If you have any of these conditions, discuss with your doctor how Lupron 14 Days Kit (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lupron 14 Days Kit (Leuprolide), and whether any special monitoring is needed.

Seizures: People using Lupron 14 Days Kit (Leuprolide) have reported experiencing seizures. People who have a history of Epilepsy, medical conditions that increase the risk of seizures, and are taking medications that increase the risk of seizures may be more likely to experience this effect, however people with none of these conditions have also reported seizures. If you have a history of seizures, discuss with your doctor how Lupron 14 Days Kit (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lupron 14 Days Kit (Leuprolide), and whether any special monitoring is needed.

If you experience a seizure, get emergency medical help.

Starting treatment: During the first few weeks of treatment with Lupron 14 Days Kit (Leuprolide), you may notice that your signs and symptoms temporarily get worse. This is due to a sudden increase in hormones that will normalize once the right dose for you has been found.

Urinary problems: People with problems urinating due to blockage or narrowing along the urinary tract (obstructive uropathy) may find that starting Lupron 14 Days Kit (Leuprolide) makes this symptom worse initially. If you have problems with urination, discuss with your doctor how Lupron 14 Days Kit (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lupron 14 Days Kit (Leuprolide), and whether any special monitoring is needed.

Pregnancy: Lupron 14 Days Kit (Leuprolide) should not be used during pregnancy. A non-hormonal method of birth control (e.g., condom, diaphragm, IUD) should be used during treatment. If you become pregnant during treatment, notify your doctor as soon as possible.

Breast-feeding: It is not known if Lupron 14 Days Kit (Leuprolide) passes into breast milk. If you are a breast-feeding mother and are taking Lupron 14 Days Kit (Leuprolide), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.