Norditropin Nordiflex

The recommended dose depends on the reason Norditropin Nordiflex (Somatropin) is being used and body weight of the child being treated. Your doctor will determine the appropriate dose of Norditropin Nordiflex (Somatropin) to be injected.

Norditropin Nordiflex (Somatropin) is injected subcutaneously (under the skin), once a day, at approximately the same time every day. It is important to use a different injection site each day in order to minimize the risk of fat wasting at the site of injection.

If you are using Norditropin Nordiflex (Somatropin) at home, your doctor will ensure that you understand exactly how to use it. Make sure you ask any and all questions necessary to ensure that you use it exactly as prescribed. Please refer to the package insert for details on proper injection procedures. It is important to visit your doctor regularly during therapy to ensure that the medication is working safely and effectively.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Norditropin Nordiflex (Somatropin) exactly as prescribed by your doctor. If you miss a dose, , skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Norditropin Nordiflex (Somatropin) in the refrigerator until the first injection. Do not allow Norditropin Nordiflex (Somatropin) to freeze. After the first injection, the pre-filled pen may be stored in the refrigerator for up to 4 weeks or at room temperature for up the 3 weeks. After this time, any remaining medication in the pen should be discarded safely and a new pen started. Protect the pre-filled pens from light and keep them out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

5 mg/1.5 mL
Each 1.5 mL of sterile solution for injection contains 5 mg of Norditropin Nordiflex (Somatropin). Nonmedicinal ingredients: histidine, poloxamer 188, phenol, mannitol, hydrochloric acid or sodium hydroxide, and water for injection.

10 mg/1.5 mL
Each 1.5 mL of sterile solution for injection in the pre-filled pen, contains 10 mg of Norditropin Nordiflex (Somatropin). Nonmedicinal ingredients: histidine, poloxamer 188, phenol, mannitol, hydrochloric acid or sodium hydroxide, and water for injection.

15 mg/1.5 mL
Each 1.5 mL of sterile solution for injection in the pre-filled pen, contains 15 mg of Norditropin Nordiflex (Somatropin). Nonmedicinal ingredients: histidine, poloxamer 188, phenol, mannitol, hydrochloric acid or sodium hydroxide, and water for injection.

Do not take Norditropin Nordiflex (Somatropin) if you:

• are allergic to Norditropin Nordiflex (Somatropin) or any ingredients of the medication
• have active cancer
• have an active brain tumour
• have an acute illness due to complications of surgery
• have closed epiphyses (growth plates)
• have just had a serious accident
• have Prader-Willi syndrome and are severely obese, have a history of upper airway blockage or Sleep Apnea, or have severe breathing problems
• have respiratory (breathing) failure
• have vision problems due to long-term effects of Diabetes (diabetic retinopathy)

Norditropin Nordiflex (Somatropin) should be stopped at the time of kidney transplantation.

There may be an interaction between Norditropin Nordiflex (Somatropin) and any of the following:

• corticosteroids (e.g., cortisone, Prednisone)
• diabetes medications (e.g., Canagliflozin, chlorpropamide, Glyburide, insulin, Metformin, Rosiglitazone, Sitagliptin)
• estrogens (e.g., conjugated estrogen, Estradiol, ethinyl estradiol)
• thyroid replacements (e.g., dessicated thyroid, Levothyroxine)

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Norditropin Nordiflex (Somatropin). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Norditropin Nordiflex (Somatropin).

Blood pressure: Some people using Norditropin Nordiflex (Somatropin) may experience increased blood pressure inside the brain. Signs and symptoms of this condition include severe, ongoing headache, vision changes, nausea, and vomiting. If any of these occur, talk to your doctor or your child’s doctor as soon as possible.

Cancer: There may be an increased risk of tumour growth, both cancerous and non-cancerous, when growth hormone is used by survivors of childhood cancer.

If your child complains of Headaches, vision changes, patches of skin that have changed colour or changes in behavior, contact your child’s doctor as soon as possible.

Diabetes: Norditropin Nordiflex (Somatropin) may cause an increase in blood sugar levels, and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Norditropin Nordiflex (Somatropin). If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Norditropin Nordiflex (Somatropin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Norditropin Nordiflex (Somatropin), and whether any special monitoring is needed.

Hypothyroidism (low level of Thyroid hormone): If you have uncontrolled hypothyroidism, treatment with Norditropin Nordiflex (Somatropin) may not work as well as it could. Discuss with your doctor how Norditropin Nordiflex (Somatropin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Norditropin Nordiflex (Somatropin), and whether any special monitoring is needed.

Treatment with Norditropin Nordiflex (Somatropin) may trigger hypothyroidism. If you experience unexplained weight gain, muscle aches or stiffness, constipation, dry skin, or fatigue, this may be a result of too little thyroid hormone and you should contact your doctor as soon as possible.

Pancreatitis: In rare instances, children using Norditropin Nordiflex (Somatropin) experience inflammation of the pancreas. If your child has a history of pancreatitis, discuss with your doctor how Norditropin Nordiflex (Somatropin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Norditropin Nordiflex (Somatropin), and whether any special monitoring is needed.

Report signs of pancreatitis such as abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, or swollen abdomen to your doctor immediately.

Prader-Willi Syndrome: Children who have been diagnosed with Prader-Willi syndrome may experience breathing difficulties while using Norditropin Nordiflex (Somatropin). Rarely, these breathing difficulties may be fatal. This is more likely if the child is obese, already has breathing problems or has an infection. The breathing difficulties may include sleep apnea (not breathing while sleeping) or new or increased snoring.

Pregnancy: Norditropin Nordiflex (Somatropin) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Norditropin Nordiflex (Somatropin), contact your doctor immediately.

Breast-feeding: It is not known if Norditropin Nordiflex (Somatropin) passes into breast milk. If you are a breast-feeding mother and are taking Norditropin Nordiflex (Somatropin), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Seniors: The safety and effectiveness of using Norditropin Nordiflex (Somatropin) have not been established for adults over 65 years of age.