Orfenace

The recommended adult dose of orphenadrine to be taken by mouth, is 100 mg twice daily, in the morning and evening. It may be taken with or without food. The recommended injectable dose is 60 mg injected into a vein or a muscle.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to use Orfenace (Orphenadrine-citrate) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Orfenace (Orphenadrine-citrate) at room temperature. Protect it from heat and moisture. Protect the injectable from from light. Keep all forms of Orfenace (Orphenadrine-citrate) out of the reach of children.

Orfenace (Orphenadrine-citrate) is available under multiple brand names and/or in several different forms. Any specific brand name of Orfenace (Orphenadrine-citrate) may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does Orfenace (Orphenadrine-citrate) come in?"

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Each white, round biconvex tablet contains Orphenadrine Citrate 100 mg. Nonmedicinal ingredients: calcium stearate, colloidal silicon dioxide, lactose, and microcrystalline cellulose.

Do not take orphenadrine if you:

• are allergic to orphenadrine or any ingredients of the medication
• are experiencing cardiospasm
• have an enlarged prostate
• have bladder neck obstruction
• have Glaucoma
• have Myasthenia Gravis
• have pyloric or duodenal obstruction (blockage in the upper digestive system)
• have stenosing peptic ulcers

There may be an interaction between orphenadrine and any of the following:

• alcohol
• anticholinergic medications (e.g., atropine, scopolomine)
• antihistamines (e.g., Chlorpheniramine, Diphenhydramine, Hydroxyzine)
• antipsychotics (e.g., Haloperidol, Quetiapine, risperidol)
• Baclofen
• barbiturates (e.g., butalbital, Phenobarbital)
• benzodiazepines (e.g., Clonazepam, Diazepam, Lorazepam)
• Benztropine
• brimonidine
• Buprenorphine
• Buspirone
• Carbamazepine
• Dimenhydrinate
• droperidol

• Gabapentin
• ipratropium
• Lamotrigine
• Levetiracetam
• MAO inhibitors (e.g., Maprotiline, Phenelzine, Moclobemide)
• methocarbamol
• narcotic pain relievers (e.g,. Codeine, Fentanyl, Morphine)
• Phenytoin
• Pimozide
• potassium chloride
• propoxyphene
• St. John's wort
• Tramadol
• tricyclic antidepressants (e.g., Amitriptyline, Clomipramine, Desipramine, Nortriptyline)
• valerian
• Zopiclone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Orfenace (Orphenadrine-citrate). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, decongestants, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Orfenace (Orphenadrine-citrate).

Contact lenses: Orphenadrine may make the eyes dry, resulting in discomfort or blurred vision if you wear contact lenses.

Dependence: Physical dependence, psychological dependence, and abuse have occurred with the use of orphenadrine. People with a history of past or current Substance Use Problems may be at greater risk of developing abuse or addiction while taking Orfenace (Orphenadrine-citrate).

If you have a history of drug or alcohol use problems, discuss with your doctor how Orfenace (Orphenadrine-citrate) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Orfenace (Orphenadrine-citrate), and whether any special monitoring is needed.

Drowsiness/reduced alertness: Orphenadrine may cause temporary dizziness and lightheadedness. Do not drive, operate machinery, or engage in any potentially hazardous activities until you determine how Orfenace (Orphenadrine-citrate) affects you

Heart disease: Orphenadrine may make the symptoms of certain heart problems worse. If you have coronary insufficiency, irregular heartbeat (Arrhythmias), or fast heart rate, discuss with your doctor how Orfenace (Orphenadrine-citrate) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Orfenace (Orphenadrine-citrate), and whether any special monitoring is needed.

Kidney function: The kidneys help to remove orphenadrine from the body. If you have reduced kidney function or Kidney Disease, discuss with your doctor how Orfenace (Orphenadrine-citrate) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Orfenace (Orphenadrine-citrate), and whether any special monitoring is needed.

Liver function: The liver helps to remove orphenadrine from the body. If you have reduced liver function or liver disease, discuss with your doctor how Orfenace (Orphenadrine-citrate) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Orfenace (Orphenadrine-citrate), and whether any special monitoring is needed.

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Pregnancy: Orfenace (Orphenadrine-citrate) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Orfenace (Orphenadrine-citrate), contact your doctor immediately.

Breast-feeding: It is not known if orphenadrine passes into breast milk. If you are a breast-feeding mother and are taking Orfenace (Orphenadrine-citrate), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Orfenace (Orphenadrine-citrate) have not been established for children.

Seniors: Orphenadrine is generally not recommended for people who are over the age of 65 due to the increased risk of side effects such as drowsiness and dizziness.