Progesterone

Amenorrhea: The usual recommended dose is 5 to 10 mg injected into a muscle once daily for 6 to 8 days.

Abnormal bleeding from the vagina: The usual recommended dose is 5 to 10 mg injected into a muscle once daily for 6 days.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important Progesterone be given exactly as recommended by your doctor. If you miss an appointment to receive progesterone injection, contact your doctor as soon as possible to reschedule your appointment.

Store Progesterone at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

In addition to its desired action, this medication may cause some adverse effects, notably: it may cause headaches; it may cause stomach ache; it may cause drowsiness or dizziness - use caution when getting up from a lying or sitting position and use caution if driving; it may affect menstruation (irregular or absence of menses); it may cause your breasts to feel swollen and tender. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.

Each mL of injection contains progesterone 50 mg. Nonmedicinal ingredients: benzyl alcohol 10% (as a preservative) and sesame oil.

Do not use Progesterone if you:

• are allergic to progesterone or any ingredients of Progesterone
• had a miscarriage and the doctor suspects some tissue is still in the uterus
• have a history of Blood Clots (e.g., pulmonary Embolism, deep vein thrombosis), Stroke related to a blood clot, inflammation of the veins (Thrombophlebitis), or blood clotting disorders
• have abnormal vaginal bleeding that has not been checked by a doctor
• have known or suspected Breast Cancer

Progesterone should not be used to test for pregnancy.

There may be an interaction between progesterone and any of the following:

• barbiturates (e.g., Phenobarbital)
• Carbamazepine
• Colchicine
• dabigatran
• Everolimus
• ketoconazole
• Phenytoin
• rifabutin
• rifampin
• Topotecan

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Progesterone. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Progesterone.

Drowsiness/reduced alertness: Temporary and occasional dizziness may occur for some people after taking progesterone. If the medication affects you in this way, avoid activities requiring concentration, good coordination, or reflex action such as driving or operating machinery.

Pregnancy: Do not take progesterone during pregnancy, especially during the first 4 months. If you become pregnant while taking Progesterone, contact your doctor immediately.

Breast-feeding: Progesterone passes into breast milk. If you are a breast-feeding mother and are taking progesterone, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

This medication is typically used only once a day. However, your pharmacist may have suggested a different schedule that is more appropriate for you. Important: Follow the instructions on the label. Do not use more of this product, or more often, than prescribed. If you forget a dose, contact your pharmacist. This medication should not be taken with food. It is best taken on an empty stomach, one hour before or 2 hours after a meal. Information on this sheet does not apply when this medication is administered vaginally for infertility treatments or during pregnancy.