Maxalt Rpd

The recommended adult starting dose of Maxalt Rpd (Rizatriptan) is 5 mg. In some cases, a starting dose of 10 mg may be used. The dose should be taken at the first sign of migraine headache pain. If the migraine headache comes back after being relieved, another dose (5 mg to 10 mg) may be taken no sooner than 2 hours after the first dose was taken.

The maximum recommended single dose is 10 mg. No more than 20 mg of Maxalt Rpd (Rizatriptan) should be taken in any 24-hour period. If your headache pain is different from your usual migraines, do not take Maxalt Rpd (Rizatriptan) and call your doctor. Maxalt Rpd (Rizatriptan) is not to be used for headache prevention.

It is important to take Maxalt Rpd (Rizatriptan) exactly as prescribed by your doctor.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Store Maxalt Rpd (Rizatriptan) at room temperature, protect it from moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

In addition to its desired action, this medication may cause some adverse effects, notably: it may cause drowsiness or dizziness - use caution when getting up from a lying or sitting position and use caution if driving; it may cause unusual tiredness; it may cause nausea or, rarely, vomiting; it may cause a feeling of tightness in your chest. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.

5 mg
Each white-to-off-white, round, rapidly disintegrating tablet (wafer), with a flat or slightly irregular surface, engraved with a modified triangle on one side, and with a peppermint flavour, contains Maxalt Rpd (Rizatriptan) 5 mg (corresponding to 7.265 mg of the benzoate salt). Nonmedicinal ingredients: aspartame, gelatin, glycine, mannitol, and peppermint flavour.

10 mg
Each white-to-off-white, round, rapidly disintegrating tablet (wafer), with a flat or slightly irregular surface, engraved with a modified square on one side, and with a peppermint flavour, contains Maxalt Rpd (Rizatriptan) 10 mg (corresponding to 14.53 mg of the benzoate salt). Nonmedicinal ingredients: aspartame, gelatin, glycine, mannitol, and peppermint flavour.

Do not take Maxalt Rpd (Rizatriptan) if you:

• are allergic to Maxalt Rpd (Rizatriptan) or any ingredients of Maxalt Rpd (Rizatriptan)
• do not have a clear diagnosis of migraine
• have Angina (chest pain), including Prinzmetal's angina (coronary vasospasm)
• have blood vessel disease (e.g., ischemic bowel disease, Raynaud's syndrome)
• have certain types of migraine headaches (including hemiplegic, ophthalmoplegic, or basilar migraine)
• have had a Heart Attack
• have had a Stroke or Transient Ischemic Attack (TIA)
• have heart disease (e.g., atherosclerosis, heart valve disease, abnormal heart rhythms, congenital heart disease)
• have high blood pressure that is severe or not under control
• have severely reduced liver function
• have taken another 5-hydroxytryptamine agonist (i.e., Almotriptan, Eletriptan, Frovatriptan, Naratriptan, Sumatriptan, Zolmitriptan) in the previous 24 hours
• have taken any medications belonging to the class of medications known as MAO inhibitors (see "What other drugs could interact with Maxalt Rpd (Rizatriptan)?" below) in the previous 2 weeks
• have taken an ergotamine-containing or ergot-type medication (such as Dihydroergotamine, ergotamine, or methysergide) in the past 24 hours

There may be an interaction between Maxalt Rpd (Rizatriptan) and any of the following:

• amphetamines (e.g., Dextroamphetamine, Lisdexamfetamine)
• antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
• Bromocriptine
• Buspirone
• Cabergoline
• Cyclobenzaprine
• Doxepin
• ergotamine-containing or ergot-type medication if taken at the same time or within the previous 24 hours (e.g., dihydroergotamine or methysergide)
• Fentanyl
• lithium
• Meperidine
• methylene blue
• Mirtazapine
• monoamine oxidase inhibitors if taken at the same time or within 14 days of taking Maxalt Rpd (Rizatriptan) (e.g., Phenelzine, Tranylcypromine, Selegiline, Moclobemide, Rasagiline)
• other 5-hydroxytryptamine agonists if taken at the same time or within the previous 24 hours (e.g., sumatriptan, naratriptan, zolmitriptan)
• Propranolol
• St. John's wort
• serotonin antagonists (e.g., Granisetron, Ondansetron)
• serotonin/norepinephrine reuptake inhibitors (SNRI antidepressants; e.g., Duloxetine, Desvenlafaxine, venlafaxine)
• selective serotonin reuptake inhibitors (SSRI antidepressants; e.g., fluoxetine, Fluvoxamine, paroxetine, Sertraline)
• Tramadol
• Trazodone
• tricyclic antidepressants (e.g., Amitriptyline, Imipramine, Nortriptyline)
• Tryptophan
• Vilazodone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Maxalt Rpd (Rizatriptan). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Maxalt Rpd (Rizatriptan).

Allergic reactions: Rarely, severe allergic reactions to Maxalt Rpd (Rizatriptan) may occur. Because of the possibility of an allergic reaction, people who are allergic to any of the other medications in this class (5-hydroxytryptamine agonists, also called triptans) should not use Maxalt Rpd (Rizatriptan).

Blood pressure: Maxalt Rpd (Rizatriptan) may cause an increase in blood pressure. People with severe or uncontrolled high blood pressure should not take Maxalt Rpd (Rizatriptan).

Drowsiness/reduced alertness: Maxalt Rpd (Rizatriptan) may cause drowsiness or dizziness, which may impair your ability to operate a vehicle or engage in dangerous activities that require alertness.

Heart and blood vessel disease: Maxalt Rpd (Rizatriptan) may cause narrowing of the blood vessels that supply the heart and brain. This can lead to chest pain (angina), heart attacks, heart rhythm problems, stroke, transient ischemic attack (TIA or "mini-stroke"), and other heart or blood vessel problems. For this reason, Maxalt Rpd (Rizatriptan) should not be used by people with heart or blood vessel disease.

If you have certain risk factors for heart disease (e.g., high blood pressure, High Cholesterol, smoking, Obesity, Diabetes, family history of Coronary Artery Disease, Menopause, men over 40 years of age), tell your doctor.

Kidney function: You should be closely monitored by your doctor if you are on dialysis and using Maxalt Rpd (Rizatriptan).

Liver function: Maxalt Rpd (Rizatriptan) should not be used by people with severely reduced liver function. If you have moderately reduced liver function, you should be closely monitored by your doctor while taking Maxalt Rpd (Rizatriptan).

Medication overuse headaches: As with other pain relief medications, overuse of Maxalt Rpd (Rizatriptan) may lead to medication overuse headaches, or "rebound headaches" where the headache returns as the medication wears off. Avoid taking more of Maxalt Rpd (Rizatriptan) than is recommended by your doctor. If you experience more frequent headaches, contact your doctor as soon as possible.

Phenylketonuria: The rapidly-dissolving wafer form of Maxalt Rpd (Rizatriptan) contains phenylalanine.

Seizures: There have been rare reports of seizures experienced by people taking Maxalt Rpd (Rizatriptan). Most of these people had a previous history of Epilepsy or medical conditions that increase the risk of seizures. If you have a history of epilepsy or other conditions that increase the risk for seizure, you should be closely monitored by your doctor while you are taking Maxalt Rpd (Rizatriptan).

Serotonin syndrome: Maxalt Rpd (Rizatriptan) may cause a rare but potentially life-threatening condition called serotonin syndrome, especially when used with other medications that increase serotonin levels (e.g., other triptans, Fluoxetine, Paroxetine, Venlafaxine).

If you experience symptoms such as agitation, confusion, hallucinations, fast heart rate, Fever, lack of coordination, increased body temperature, overactive reflexes, nausea, vomiting, and diarrhea, get immediate medical attention.

Pregnancy: Maxalt Rpd (Rizatriptan) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Maxalt Rpd (Rizatriptan), contact your doctor immediately.

Breast-feeding: It is not known if Maxalt Rpd (Rizatriptan) passes into breast milk. If you are a breast-feeding mother and are taking Maxalt Rpd (Rizatriptan), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Maxalt Rpd (Rizatriptan) have not been established for children.

Seniors: The safety and effectiveness of Maxalt Rpd (Rizatriptan) have not been adequately studied in people over 65 years. Its use in this age group is not recommended.

For greater effectiveness and faster relief, use this product at the first sign of a migraine. Avoid touching the tablet or take it with dry hands. Place the tablet on your tongue and allow it to melt. Then swallow it with your saliva. Generally, this medication is used only as needed. Important: Follow the instructions on the label. Do not use more of this product, or more often, than prescribed. This medication may be taken with or without food.