
Viibryd
Vilazodone
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Viibryd - clinical reference
A licensed healthcare practitioner can help you understand what applies to your specific situation.
The usual starting dose of Viibryd (Vilazodone) is 10 mg taken once daily by mouth. After one week, the dose is increased to 20 mg once daily. Depending on the effectiveness and side effects of the medication, the dose may be increased after one week to 40 mg daily. The usual adult dose is 20 mg to 40 mg taken once daily.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
The effectiveness of Viibryd (Vilazodone) is affected by food. Take Viibryd (Vilazodone) with food to get the most benefit from the medication. Swallow the tablets whole with some water, do not crush or chew them.
It is important to take Viibryd (Vilazodone) exactly as prescribed by your doctor.
If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Viibryd (Vilazodone) at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
In addition to its desired action, this medication may cause some adverse effects, notably: it may cause dryness of the mouth; it may cause headaches; it may cause diarrhea; it may cause drowsiness or dizziness - use caution when getting up from a lying or sitting position and use caution if driving; it may cause nausea or, rarely, vomiting. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.
10 mg
Each film-coated, pink, oval immediate-release tablet, debossed with "10" on one side, contains 10 mg of Viibryd (Vilazodone) hydrochloride. Nonmedicinal ingredients: colloidal silicon dioxide, FD&C Red No. 40, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.
20 mg
Each film-coated, orange, oval immediate-release tablet, debossed with "20" on one side, contains 20 mg of Viibryd (Vilazodone) hydrochloride. Nonmedicinal ingredients: colloidal silicon dioxide, FD&C Yellow No. 6, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.
40 mg
Each film-coated, blue, oval immediate-release tablet, debossed with "40" on one side, contains 40 mg of Viibryd (Vilazodone) hydrochloride. Nonmedicinal ingredients: colloidal silicon dioxide, FD&C Blue No. 1, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.
Do not take Viibryd (Vilazodone) if you:
- are allergic to Viibryd (Vilazodone) or any ingredients of the medication
- have taken a monoamine oxidase inhibitor (MAO inhibitor; e.g., Phenelzine, Tranylcypromine) within the past 2 weeks
There may be an interaction between Viibryd (Vilazodone) and any of the following:
- acetylsalicylic acid (ASA)
- alcohol
- amphetamines (Dextroamphetamine, Lisdexamfetamine)
- Anagrelide
- antihistamines (e.g., cetirizine, doxylamine, Diphenhydramine, Hydroxyzine, Loratadine)
- antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
- Apalutamide
- Apixaban
- Aprepitant
- "azole" antifungals (e.g., itraconazole, ketoconazole, Voriconazole)
- benzodiazepines (e.g., Alprazolam, Diazepam, Lorazepam)
- beta-blockers (e.g., Carvedilol, Metoprolol, Propranolol)
- Bromocriptine
- Bosentan
- brimonidine
- Buprenorphine
- Bupropion
- Buspirone
- Celecoxib
- chloral hydrate
- chloroquine
- Clonidine
- Clopidogrel
- Cobicistat
- dabigatran
- Deferasirox
- Desmopressin
- dexmethylphenidate
- Dextromethorphan
- Diabetes medications (e.g., Canagliflozin, Glyburide, insulin, Metformin, Rosiglitazone)
- Digoxin
- Diltiazem
- Dipyridamole
- Disopyramide
- Edoxaban
- Entacapone
- Enzalutamide
- ergot alkaloids (e.g., ergotamine, Dihydroergotamine)
- glucosamine
- grapefruit juice
- Heparin
- Hepatitis C antivirals (dasabuvir, ombitasvir, paritaprevir)
- herbal products that affect blood clotting (e.g., cat's claw, chamomile, fenugreek, evening primrose, feverfew, garlic, ginger, ginseng, turmeric)
- HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., efavirenz, etravirine, nevirapine)
- HIV protease inhibitors (e.g., atazanavir, darunavir, lopinavir, ritonavir)
- hydroxychloroquine
- Lanreotide
- Levothyroxine
- Linezolid
- lithium
- low molecular weight heparins (e.g., Dalteparin, Enoxaparin, Tinzaparin)
- macrolide antibiotics (e.g., clarithromycin, erythromycin)
- lumacaftor and Ivacaftor
- Methadone
- methylene blue
- Methylphenidate
- Metoclopramide
- mifepristone
- Mirtazapine
- Modafinil
- monoamine oxidase inhibitors (M.O.S. e.g., Moclobemide, Rasagiline, Selegiline, tranylcypromine)
- multivitamin supplements with minerals
- muscle relaxants (e.g., Baclofen, Cyclobenzaprine, orphenadrine, methocarbamol)
- narcotic pain medications (e.g., Fentanyl, Meperidine, Morphine, Oxycodone, Tapentadol)
- non-steroidal anti-inflammatory medications (NSAIDs; e.g., Diclofenac, ibuprofen, naproxen)
- Obinutuzumab
- Octreotide
- omega-3 fatty acids
- Pasireotide
- Pentoxifylline
- Prasugrel
- protein kinase inhibitors (e.g., Ceritinib, Dabrafenib, Dasatinib, Idelalisib, imatinib, Sunitinib)
- quinine
- rifampin
- Rivaroxaban
- St. John's wort
- scopolamine
- seizure medications (e.g., Carbamazepine, Clobazam, Gabapentin, Lamotrigine, Phenobarbital, Phenytoin)
- selective serotonin reuptake inhibitors (SSRIs; e.g., Citalopram, Fluoxetine, Paroxetine, Sertraline)
- serotonin antagonists (anti-emetic medications; e.g., Granisetron, Ondansetron)
- serotonin-norepinephrine reuptake inhibitors (SNRIs; Desvenlafaxine, Duloxetine, Venlafaxine)
- siltuximab
- sulfamethoxazole
- thiazide diuretics (water pills; e.g., Hydrochlorothiazide, Indapamide, Metolazone)
- Ticagrelor
- Ticlopidine
- Tocilizumab
- tramadol
- Trazodone
- tricyclic antidepressants (e.g., Amitriptyline, Clomipramine, Desipramine, Trimipramine)
- "triptan" migraine medications (e.g., Eletriptan, rizatriptan, sumatriptan)
- Tryptophan
- valerian
- Verapamil
- vitamin E
- warfarin
- Zolpidem
- Zopiclone
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Viibryd (Vilazodone). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Viibryd (Vilazodone).
Bleeding: Viibryd (Vilazodone) may increase the risk of bleeding, especially if you are also taking medications such as acetylsalicylic acid (Asa), nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., Ibuprofen, Naproxen, Ketoprofen), or Warfarin. If you experience easy bruising, pinpoint-sized red spots on the skin, or unusual bleeding while taking Viibryd (Vilazodone), contact your doctor immediately.
Blood pressure: Viibryd (Vilazodone) can increase blood pressure. If you have uncontrolled blood pressure or a medical condition that can be affected by increased blood pressure, discuss with your doctor how Viibryd (Vilazodone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Viibryd (Vilazodone), and whether any special monitoring is needed.
Bones: Medications similar to Viibryd (Vilazodone) have been shown to increase the risk of bone fractures. Viibryd (Vilazodone) may increase the risk of bone fractures, especially if youare a senior or have Osteoporosis or other major risk factors for breaking a bone. Take extra care to avoid falls, especially if you get dizzy or have Low Blood Pressure.
Your doctor may monitor your bones while you are taking Viibryd (Vilazodone).
Drowsiness/reduced alertness: Viibryd (Vilazodone) may cause drowsiness. People taking Viibryd (Vilazodone) should avoid operating hazardous machinery (including cars) until they are certain that the medication does not impair their mental alertness, judgment, or physical coordination.
Glaucoma: Viibryd (Vilazodone) may cause the symptoms of glaucoma (increased pressure in the eye) to become worse. If you have glaucoma, discuss with your doctor how Viibryd (Vilazodone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Viibryd (Vilazodone), and whether any special monitoring is needed. Report any changes in vision to your doctor as soon as possible while you are taking Viibryd (Vilazodone).
Mental health: Viibryd (Vilazodone) may trigger mania and make behavior and thought disturbances worse for people who have mental health conditions. It may also cause symptoms of psychosis and mania for people who have not had these symptoms before. If you experience symptoms such as hallucinations, mania (feeling unusually over-excited or uninhibited), or delusional thinking, or notice them in a family member who is taking Viibryd (Vilazodone), contact your doctor as soon as possible. If you have mental health concerns, discuss with your doctor how Viibryd (Vilazodone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Viibryd (Vilazodone), and whether any special monitoring is needed.
Serotonin syndrome: Viibryd (Vilazodone) may cause a rare but potentially life-threatening condition called serotonin syndrome, especially when used with other medications that increase serotonin levels (e.g., Sumatriptan, Rizatriptan, Tramadol, St. John's wort). If you experience symptoms such as agitation, confusion, hallucinations, fast heart rate, fever, lack of coordination, increased body temperature, overactive reflexes, nausea, vomiting, and diarrhea, get immediate medical attention.
Seizure risk: Seizures are a possible side effect of most antidepressant medications. If you are at risk of seizures, discuss with your doctor how Viibryd (Vilazodone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Viibryd (Vilazodone), and whether any special monitoring is needed.
Stopping Viibryd (Vilazodone): Stopping Viibryd (Vilazodone) suddenly can cause uncomfortable and possibly dangerous effects. If you are thinking of stopping Viibryd (Vilazodone), check with your doctor or pharmacist for the best way to gradually reduce the dose before stopping completely.
Suicidal or agitated behaviour, or other behaviour changes: People taking Viibryd (Vilazodone) may feel agitated (restless, anxious, aggressive, emotional, and feeling not like themselves), or they may want to hurt themselves or others. These symptoms may occur within several weeks after people start taking Viibryd (Vilazodone). If you experience these side effects or notice them in a family member who is taking Viibryd (Vilazodone), contact your doctor immediately. Your doctor will monitor you for emotional and behavioural changes while you are taking Viibryd (Vilazodone).
Pregnancy: Viibryd (Vilazodone) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Viibryd (Vilazodone), contact your doctor immediately.
Breast-feeding: It is not known if Viibryd (Vilazodone) passes into breast milk. If you are a breast-feeding mother and are taking Viibryd (Vilazodone), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Viibryd (Vilazodone) have not been established for children. Safety studies show that people between the ages of 12 and 18 who take other medications similar to Viibryd (Vilazodone) are at increased risk of having thoughts and behavior related to self-harm and suicide. Viibryd (Vilazodone) should not be used by anyone under 18 years old.
This medication is typically used only once a day. However, your pharmacist may have suggested a different schedule that is more appropriate for you. Take it regularly and continuously to maintain its beneficial effects. It is not advisable to stop using this product suddenly, particularly if you have been on it for several weeks. If you are considering stopping the medication, talk to your pharmacist first. If you forget a dose, take it as soon as you remember -- unless it is almost time for your next dose. In that case, skip the missed dose. Do not double the next dose to catch up. This medication is more effective if taken with food. Always take it with a meal or a snack. Avoid consuming alcohol or alcohol-containing products while taking this medication.









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