Pms Ketoprofen

The recommended adult dose for rheumatoid arthritis and osteoarthritis is 150 mg to 200 mg daily. If given as a short-acting tablet, the dose should be divided into 3 or 4 equal doses throughout the day. Once the dose has been established, some people can take their daily dose in 2 equal doses. If the maintenance dose is 200 mg, then the extended-release tablet may be taken once daily.

For treatment of menstrual cramps and mild-to-moderate pain, the recommended adult dose is 25 mg to 50 mg 3 or 4 times daily as needed.

The enteric-coated tablets or sustained-release tablets should be taken 1 or 2 hours before meals or at least 2 hours after meals. Ketoprofen short-acting capsules should be taken immediately after a meal or with food to reduce stomach upset.

You should not lie down for about 15 to 30 minutes after taking the medication. If stomach upset occurs and does not go away, contact your doctor. Ketoprofen tablets and capsules should always be swallowed whole.

Rectal suppositories provide an alternative form of the medication. One suppository can be used in the morning and evening (at bedtime) with appropriate use of ketoprofen tablets throughout the day as required. Ketoprofen suppositories should only be used rectally.

The total daily dose of ketoprofen should not exceed 200 mg (includes any combination of tablets and suppositories), except during severe flare-ups of rheumatic arthritis, when the dose may be increased to a maximum of 300 mg daily. In general, to reduce the risk of side effects, the lowest dose for the shortest period of time should be used.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones given here, do not change the way that you are using the medication without consulting your doctor.

It is important to use Pms Ketoprofen exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Pms Ketoprofen at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Capsule

Pms Ketoprofen is available as a 50 mg capsule.

Enteric-coated tablets

Pms Ketoprofen is available as 50 mg and 100 mg enteric coated tablets.

Suppositories

50 mg
Each white to off-white suppository contains 50 mg of ketoprofen. Nonmedicinal ingredient: triglycerides.

100 mg
Each white to off-white suppository contains 100 mg of ketoprofen. Nonmedicinal ingredient: triglycerides.

Do not use Pms Ketoprofen if you:

• are allergic to ketoprofen or any ingredients of Pms Ketoprofen
• are allergic to Asa or other NSAIDs (e.g., Ibuprofen, Ketorolac, Diclofenac) or have had allergic symptoms (e.g., runny nose; Asthma; itchy skin rash; nasal polyps; swelling of the face, throat, or tongue) caused by these medications
• have an ulcer or an inflammatory disease of the stomach or intestines (e.g., Ulcerative Colitis)

Do not use the suppositories if you have inflammation of the rectum or anus or recent bleeding from the rectum or anus.

There may be an interaction between ketoprofen and any of the following:

• 5-ASA medications (e.g., Mesalamine, olsalzine, Sulfasalazine)
• acetylsalicylic acid (ASA)
• alcohol
• Aliskiren
• aminoglycoside antibiotics (e.g., Amikacin, gentamicin, tobramycin)
• angiotensin converting enzyme inhibitors (ACEIs; Captopril, Ramipril)
• angiotensin receptor blockers (ARBs; e.g., candasartan, Irbesartan, Losartan)
• Apixaban
• beta-adrenergic blockers (e.g., Atenolol, Propranolol, Sotalol)
• bisphosphonates (e.g., Alendronate, etidronate)
• Celecoxib
• Cholestyramine
• clopidogrel
• Colestipol
• corticosteroids (e.g., Dexamethasone, Hydrocortisone, prednisone)
• Cyclosporine
• dabigatran
• Dasatinib
• Desmopressin
• Digoxin
• Dipyridamole
• diuretics (water pills; e.g., Furosemide, Hydrochlorothiazide, Spironolactone)
• drospirenone
• glucosamine
• Haloperidol
• heparin
• herbs that may increase the risk of bleeding (e.g., cat's claw, dong quai, feverfew, garlic, ginger)
• Hydralazine
• lithium
• low-molecular-weight heparins (e.g., Dalteparin, Enoxaparin, Tinzaparin)
• Methotrexate
• multivitamin/mineral supplements
• other NSAIDs (e.g., Naproxen, ibuprofen, diclofenac)
• Obinutuzumab
• omega-3 fatty acids
• Pemetrexed
• Prasugrel
• prostaglandin eye drops (e.g., Latanoprost, Bimatoprost)
• quinolone antibiotics (e.g., ciprofloxacin, Norfloxacin, Ofloxacin)
• Rivaroxaban
• selective serotonin reuptake inhibitors (SSRIs; e.g., citalopram, Escitalopram, fluoxetine, paroxetine, sertraline)
• serotonin-norepinephrine reuptake inhibitors (SNRIs; Desvenlafaxine, Duloxetine, Venlafaxine)
• sodium phosphates
• Tacrolimus
• tenofovir
• Ticagrelor
• Ticlopidine
• tipranavir
• tricyclic antidepressants (e.g., Amitriptyline, Clomipramine, Desipramine, Trimipramine)
• vancomycin
• vitamin E
• warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Pms Ketoprofen. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Pms Ketoprofen.

HEALTH CANADA ADVISORY

June 8, 2021

Health Canada has issued new information concerning the use of non-steroidal anti-inflammatory drugs (NSAIDs). To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.

A previous advisory on non-steroidal anti-inflammatory drugs (NSAIDs) was issued on October 30, 2020.

Blood clotting: This medication may reduce the ability of the blood to clot. If you are taking anticoagulants (e.g., Warfarin, Heparin) or have Hemophilia or another blood disorder (e.g., low platelets), discuss with your doctor how Pms Ketoprofen may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Ketoprofen, and whether any special monitoring is needed. If you have a bleeding disorder, do not take Pms Ketoprofen.

Drowsiness and dizziness: Pms Ketoprofen can cause drowsiness and dizziness that may affect your ability to drive or operate machinery safely. Avoid potentially hazardous activities until you know how Pms Ketoprofen affects you.

Fluid and electrolyte balance: NSAIDs such as ketoprofen can cause fluid retention and edema (swelling). This can lead to high blood pressure or worsening of heart failure. If you have heart failure or high blood pressure, discuss with your doctor how Pms Ketoprofen may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Ketoprofen, and whether any special monitoring is needed.

Heart Attack and Stroke: This medication may be associated with an increased risk of heart attack and stroke. The risk is increased with higher total daily doses and taking the medication over long periods of time. If you have a history of heart disease (e.g., heart attack, stroke, heart failure) or have risk factors for heart disease (e.g., high blood pressure, High Cholesterol, Diabetes, smoking, Kidney Disease) discuss with your doctor how Pms Ketoprofen may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Ketoprofen, and whether any special monitoring is needed.

Infection: Pms Ketoprofen may mask the signs of infection (e.g., Fever). If you notice other symptoms of infection (e.g., painful or frequent urination, productive cough) contact your doctor.

Kidney function: Long-term use of ketoprofen may lead to a higher risk of reduced kidney function. You have a higher risk of developing kidney problems if you are a senior, take diuretics (water pills), or already have kidney disease, liver disease, or heart failure. Your doctor will monitor your kidney function with blood tests if you take Pms Ketoprofen for a long period of time.

Liver problems: Liver disease or reduced liver function may cause Pms Ketoprofen to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Pms Ketoprofen may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Ketoprofen, and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Pms Ketoprofen.

Ketoprofen may affect your liver function or cause liver problems. Your doctor will monitor your liver function with blood tests if you take Pms Ketoprofen for a long period of time.

If you experience symptoms of liver problems (e.g., nausea, vomiting, feeling tired, yellowing of the skin or eyes) contact your doctor immediately. If you have liver problems, discuss with your doctor how Pms Ketoprofen may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Skin reactions: Pms Ketoprofen can cause skin reactions, some of which may be severe. If you experience a skin rash, especially where the skin is blistering or peeling, stop taking Pms Ketoprofen and contact your doctor.

Pms Ketoprofen may make your skin more sensitive to sunlight (including sunlamps) and may cause Sunburn, skin blisters, and skin redness, itching, or discoloration. If you have a reaction from the sun while taking Pms Ketoprofen, contact your doctor.Ulcers or bleeding in the stomach or intestines: Ketoprofen can cause stomach ulcers, perforations (holes), and bleeding from the stomach. These complications can occur at any time without warning, and are sometimes severe enough to require immediate medical attention. The risk of ulcers and bleeding increases if you are taking higher doses of ketoprofen for longer periods of time.

Other factors that increase the risk of these complications include drinking excessive amounts of alcohol, increased age, smoking, poor health, H pylori infection, and taking certain medications (e.g., warfarin, ASA, Clopidogrel, Prednisone, Citalopram, Fluoxetine, Paroxetine, Sertraline).

If you currently have ulcers that are bleeding in the stomach or intestines, or have an inflammatory bowel disease (e.g., Crohn's Disease, ulcerative colitis), you should not take Pms Ketoprofen. If you have a history of these conditions, discuss with your doctor how Pms Ketoprofen may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Ketoprofen, and whether any special monitoring is needed.

Stop taking the medication and get immediate medical attention if you experience symptoms or signs of stomach ulcers or bleeding in the stomach (black, tarry stools; blood in stools; stomach pain; vomiting blood or material that looks like coffee grounds). These reactions can occur at any time during treatment without warning.

Pregnancy: Pms Ketoprofen should not be used during pregnancy. If you become pregnant while taking Pms Ketoprofen, contact your doctor immediately.

Breast-feeding: Pms Ketoprofen may pass into breast milk. If you are a breast-feeding mother and are taking ketoprofen, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using this medication have not been established for children under 12 years of age.

Seniors: If you are a senior, you may have a higher risk of experiencing side effects from Pms Ketoprofen. You should use the lowest effective dose under close medical supervision.