Aldactone

The recommended dose of Aldactone (Spironolactone) for adults ranges from 25 mg to 400 mg daily depending on the condition being treated. It may be taken in single or divided doses.For children with edema (fluid retention) associated with congestive heart failure, cirrhosis of the liver, or nephrotic syndrome, the daily dose is based on body weight and is given in single or divided doses.Since Aldactone (Spironolactone) increases urine output, it is better to take it early in the day (with breakfast if you are taking a once-daily dose, or with breakfast and lunch if you are taking divided doses). Aldactone (Spironolactone) may be taken with or without food. If stomach upset occurs, take the medication with food.Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.It is important that Aldactone (Spironolactone) be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.Store Aldactone (Spironolactone) at room temperature, protect it from heat and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

In addition to its desired action, this medication may cause some adverse effects, notably: it may decrease your appetite; it may cause headaches; occasionally, it may cause breast development in men; it may affect menstruation (irregular or absence of menses); it may cause your breasts to feel swollen and tender; it may cause drowsiness - use caution when driving. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.

25 mg
Each light yellow, round, biconvex, film-coated tablet, debossed "ALDACTONE" and "25" on one face and "SEARLE" and "1001" on the other face and with peppermint odour, contains Aldactone (Spironolactone) 25 mg. Nonmedicinal ingredients: calcium sulfate, carnauba wax, cornstarch, hypromellose, magnesium stearate, opaspray M-1-2042, peppermint flavouring, polyethylene glycol 400, povidone, and stearic acid.

100 mg
Each peach, round, biconvex, scored, film-coated tablet, debossed "ALDACTONE" and "100" on one face and "SEARLE" and "1031" on the other (scored) face and with peppermint odour, contains Aldactone (Spironolactone) 100 mg. Nonmedicinal ingredients: calcium sulfate, carnauba wax, cornstarch, hypromellose, magnesium stearate, opaspray M-1-2668, peppermint flavouring, polyethylene glycol 400, povidone, and stearic acid.

Do not take Aldactone (Spironolactone) if you:

• are allergic to Aldactone (Spironolactone) or any ingredients of the medication
• are unable to produce urine
• have Addison's Disease
• have high blood levels of potassium
• have rapidly worsening kidney function
• have significantly reduced kidney function
• are using Eplerenone, Heparin, or a low molecular weight heparin
• are pregnant
• are breast-feeding

There may be an interaction between Aldactone (Spironolactone) and any of the following:

• Abiraterone
• Aldesleukin
• alcohol
• alpha/ beta agonists (e.g., Epinephrine, norepinephrine)
• alpha agonists (e.g., Clonidine, methyldopa)
• alpha blockers (e.g., Alfuzosin, Doxazosin, Tamsulosin)
• amifostine
• amphetamines (e.g., Dextroamphetamine, lisdexamphetamine)
• angiotensin II antagonists (e.g., Candesartan, Valsartan)
• angiotensin-converting enzyme inhibitors (ACE inhibitors; e.g., Captopril, Enalapril, Lisinopril, Ramipril)
• Atorvastatin
• barbiturates (e.g., Phenobarbital, butalbital)
• beta-adrenergic blockers (e.g., Atenolol, Propranolol, Sotalol)
• brimonidine
• calcium channel blockers (e.g., Amlodipine, Diltiazem, Nifedipine, Verapamil)
• Canagliflozin
• Cholestyramine
• ciprofloxacin
• corticosteroids (e.g., Prednisone, Dexamethasone)
• Cyclosporine
• Dapagliflozin
• diazoxide
• Digoxin
• other diuretics (water pills; e.g., Amiloride, Furosemide, Hydrochlorothiazide)
• dropspirenone
• Duloxetine
• eplerenone
• Guanfacine
• heparin
• levodopa
• lithium
• low molecular weight heparins (e.g., Dalteparin, Enoxaparin, Tinzaparin)
• Methylphenidate
• Minoxidil
• Mitotane
• monoamine oxidase inhibitors (M.O.S. e.g., Moclobemide, Phenelzine, Rasagiline, Selegiline, Tranylcypromine)
• narcotic medications (e.g., Codeine, Morphine)
• nitrates (e.g., Nitroglycerin, isosorbide dinitrate, isosorbide mononitrate)
• Nitrofurantoin
• nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., Diclofenac, Ibuprofen, Ketorolac, Naproxen)
• Obinutuzumab
• Pentoxifylline
• phosphodiesterase 5 inhibitors (e.g., Sildenafil, Tadalafil, Vardenafil)
• potassium-containing medications, supplements, or salt-substitutes (e.g., potassium chloride, potassium citrate, potassium gluconate, potassium iodide, potassium phosphate)
• Quetiapine
• quinidine
• salicylates (e.g., Asa, salsalate)
• Risperidone
• Rituximab
• sodium phosphates
• Tacrolimus
• Tolvaptan
• Trimethoprim
• Yohimbine

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Aldactone (Spironolactone). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Aldactone (Spironolactone).

Breast enlargement in men: Men may develop breast enlargement with the use of Aldactone (Spironolactone). If this occurs, tell your doctor. In the great majority of cases, breast enlargement disappears once the medication is stopped.

Drowsiness and dizziness: Aldactone (Spironolactone) may cause drowsiness or dizziness, affecting your ability to drive or operate machinery.

Avoid these and other hazardous tasks until you have determined how Aldactone (Spironolactone) affects you. Aldactone (Spironolactone) may also cause dizziness or lightheadedness when moving from a lying or sitting to an upright position.

Alcohol can add to the drowsiness caused by this medication.

Potassium: Aldactone (Spironolactone) may cause high potassium levels if potassium intake is too high. Do not take potassium supplements, follow a diet rich in potassium, or use salt substitutes containing potassium while taking Aldactone (Spironolactone). People with reduced kidney function, seniors, and people with Diabetes are more at risk of developing high potassium levels.

Fluid and electrolyte balance: Aldactone (Spironolactone) may cause the levels of electrolytes such as potassium, sodium, and chloride in the blood to change while taking this medication. If you experience symptoms of fluid and electrolyte imbalance such as muscle pains or cramps; dry mouth; numb hands, feet, or lips; or racing heartbeat, contact your doctor as soon as possible. Your doctor will do blood tests regularly to monitor the levels of these electrolytes in your blood while you are taking Aldactone (Spironolactone).

Liver function: Small changes to electrolytes and fluid in the body can cause large changes to liver function. If you have liver problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Aldactone (Spironolactone), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Aldactone (Spironolactone).

Pregnancy: Aldactone (Spironolactone) crosses the placenta and may affect the developing baby if taken by a woman when she is pregnant. Aldactone (Spironolactone) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Aldactone (Spironolactone) talk to your doctor about the potential benefits and risks of taking Aldactone (Spironolactone) during pregnancy.

Breast-feeding: Aldactone (Spironolactone) passes into breast milk. If you are a breast-feeding mother and are taking Aldactone (Spironolactone), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

This medication is typically used only once a day. However, your pharmacist may have suggested a different schedule that is more appropriate for you. Important: Follow the instructions on the label. Do not use more of this product, or more often, than prescribed. It must be used regularly and continuously to maintain its beneficial effects. Be sure to keep an adequate supply on hand. If you forget a dose, take it as soon as you remember -- unless it is almost time for your next dose. In that case, skip the missed dose. Do not double the next dose to catch up. This medication may be taken with or without food, but always the same way (always with or always without food). Consuming alcohol may modify the effect of this product. Limit alcohol consumption during treatment.