Nitro

The usual dose of Nitro patches varies according to need. The patch is usually applied in the morning and taken off 12 to 14 hours later (leaving 10 to 12 hours overnight without the patch).

The patch may be applied to any convenient skin area – recommended sites include the upper arm, back, shoulders, or chest. Use a different application site each time. A suitable area may be shaved if necessary. Do not apply the patch to the ends of the arms or legs. Wash your hands thoroughly after application. Following use, discard the patch in a manner that prevents accidental application or ingestion by curious pets or children.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use Nitro exactly as prescribed by your doctor. If you miss a dose, apply a patch as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Nitro at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

0.2 mg/hr
Each 7.4 cm2 translucent rectangular patch with rounded corners, printed with white ink, on a removable release liner, contains 20.7 mg of Nitro released at a rate of 0.2 mg per hour.

0.4 mg/hr
Each 14.8 cm2 translucent rectangular patch with rounded corners, printed with white ink, on a removable release liner contains 41.4 mg of Nitro, released at a rate of 0.4 mg per hour.

0.6 mg/hr
Each 22.2 cm2 translucent rectangular patch with rounded corners, printed with white ink, on a removable release liner contains 62.2 mg of Nitro released at a rate of 0.6 mg per hour.

0.8 mg/hr
Each 29.6 cm2 translucent rectangular patch with rounded corners, printed with white ink, on a removable release liner contains 82.9 mg of Nitro, released at a rate of 0.8 mg per hour.

Do not use Nitro if you:

• are allergic to Nitro or any ingredients of the medication
• are allergic to the adhesive used in Nitro patches
• are allergic to other nitrates or nitrites
• have acute circulatory failure associated with severe lowering of blood pressure (states of collapse or shock)
• have extremely Low Blood Pressure
• have increased eye pressure (Glaucoma)
• have increased pressure within the head (e.g., after an accident)
• have reduced heart function due to obstruction (e.g., narrowing of the heart valves)
• have severe Anemia
• have severe dizziness when getting up from a sitting or lying down position
• are using the Erectile Dysfunction medications called PDE-5 inhibitors (e.g., Sildenafil, Tadalafil, or Vardenafil)
• are taking the medication Riociguat

There may be an interaction between Nitro and any of the following:

• alcohol
• Aldesleukin
• Aliskiren
• alpha-agonists (e.g., Clonidine, methyldopa)
• alpha-blockers (e.g., Alfuzosin, Doxazosin, Tamsulosin)
• amifostine
• Amiodarone
• angiotensin converting enzyme inhibitors (ACEIs; Captopril, Enalapril, Ramipril)
• angiotensin receptor blockers (ARBs; e.g., Candesartan, Irbesartan, Losartan)
• second generation anti-psychotics (e.g., Clozapine, Olanzapine, Quetiapine, Risperidone)
• barbiturates (e.g., butalbital, pentobarbital, Phenobarbital)
• beta-adrenergic blockers (e.g., Atenolol, Propranolol, Sotalol)
• brimonidine
• Bromocriptine
• Cabergoline
• calcium channel blockers (e.g., Amlodipine, Diltiazem, Nifedipine, Verapamil)
• clonidine
• conivaptan
• Dapsone
• diazoxide
• Dipyridamole
• diuretics (water pills; e.g., Furosemide, Hydrochlorothiazide, triamterene)
• Duloxetine
• Eplerenone
• ergot alkaloids (e.g., Dihydroergotamine, ergonovine, ergotamine, methylergonovine)
• Heparin
• Hydralazine
• Guanfacine
• levodopa
• Minoxidil
• other nitrates (e.g., Nitro, isosorbide dinitrate, isosorbide mononitrate)
• Obinutuzumab
• Pentoxifylline
• phosphodiesterase 5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)
• prilocaine
• riociguat
• Ropinirole
• Rosiglitazone
• Selegiline
• sodium nitrite
• tetracaine
• Tizanidine
• tolcapone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Nitro. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Nitro.

Acute angina attacks: Nitro patches are not intended for immediate relief of acute attacks of angina. Sublingual (under the tongue) Nitro preparations (spray or tablets) should be used for this purpose.

Dizziness/reduced alertness: People using Nitro may experience faintness or dizziness and reduced reaction time when driving or operating machinery, especially at the start of treatment. Avoid these and other hazardous tasks until you have determined how Nitro affects you.

Heart disease: The benefits and safety of using the Nitro patch have not been established for people who have had an acute heart attack or have Congestive Heart Failure.

Low blood pressure: Headaches or symptoms of low blood pressure such as weakness or dizziness, particularly when getting up suddenly from a sitting or lying down position, may result from taking too much Nitro. If these symptoms occur, your doctor may reduce the dose or have you stop using the Nitro patch. People who might be negatively affected by low blood pressure should use Nitro with caution. If you take diuretics or have preexisting low blood pressure, you may be at an increased risk of experiencing this effect.

Symptom changes: If your symptoms of angina increase at any time (including during the period of the day that you aren't taking the medication), be sure to tell your doctor.

Tolerance: People who use Nitro may develop tolerance to the medication, resulting in it not working as well. Tolerance to other nitrates or nitrites can also happen, especially if a medication-free period is not observed each day. As tolerance to Nitro patches develops, the effect of fast-acting sublingual (under the tongue) Nitro is also somewhat reduced.

Pregnancy: Nitro has not been studied for use by pregnant women and should not be used during pregnancy unless the benefits outweigh the risks. Be sure to tell your doctor if you are pregnant or planning to become pregnant. If you become pregnant while using Nitro, inform your doctor as soon as possible.

Breast-feeding: It is not known if Nitro passes into breast milk. If you are a breast-feeding mother and are taking Nitro, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of Nitro for children have not been established.

<p> Nitro (<a href="/drug/trinipatch">Nitro</a>) belongs to the class of medications called <i>antianginals</i>. Nitro patches are used alone or in combination with other medications to <b>prevent Angina attacks (chest pain). </b>Nitro reduces the number of angina attacks by relaxing blood vessels and increasing the oxygen and blood supply to the heart. The Nitro patch is not intended for immediate relief of angina.</p><p> <b>Nitro may be available under multiple brand names and/or in several different forms.</b> Any specific brand name of Nitro may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Nitro may not be used for all of the conditions discussed here.</p><p> <b>Your doctor may have suggested Nitro for conditions other than those listed in these drug information articles.</b> If you have not discussed this with your doctor or are not sure why you are being given Nitro, speak to your doctor. <b>Do not stop using Nitro without consulting your doctor.</b></p><p><b>Do not give Nitro to anyone else, even if they have the same symptoms as you do.</b> It can be harmful for people to use Nitro if their doctor has not prescribed it.</p>