Pms Sildenafil R

The recommended adult dose of sildenafil for pulmonary hypertension is 20 mg 3 times daily. Doses should be taken approximately 6 to 8 hours apart.

Sildenafil may be taken with or without food.

The solution for injection is used to continue treatment with sildenafil when a person with pulmonary hypertension is temporarily unable to take sildenafil by mouth. The maximum dose of this form of sildenafil is 10 mg given by intravenous (into a vein) injection 3 times a day. This dose of sildenafil is approximately equal in activity to 20 mg of sildenafil taken by mouth.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important that Pms Sildenafil R be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Pms Sildenafil R at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

In addition to its desired action, this medication may cause some adverse effects, notably: it may cause headaches; it may cause sleep disturbances or insomnia; it may cause indigestion; it may cause nosebleeds; it may cause redness of the face; it may temporarily affect your ability to perceive colour. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.

20 mg
Each white-to-off-white, round, biconvex, film-coated tablet, debossed with "SD 20" on one side and plain on other, contains 20 mg sildenafil, as sildenafil citrate. Nonmedicinal ingredients: colloidal silicon dioxide, corn starch, lactose, magnesium stearate, povidone, and sodium starch glycolate. Tablet coating: hydroxypropyl methylcellulose, polyethylene glycol, sodium lauryl sulphate, and titanium dioxide.

Do not take sildenafil if you:

• are allergic to sildenafil or any ingredients of the medication
• are taking Nitroglycerin (sprays, ointments, skin patches or pastes, tablets) or other nitrate medications (e.g., isosorbide dinitrate or isosorbide mononitrate) due to the risk of developing dangerously Low Blood Pressure
• have pulmonary hypertension caused by sickle cell Anemia (a red blood cell abnormality)
• have a history of vision problems related to nerve damage to the Retin A caused by decreased blood flow
• are taking the medications ketoconazole, itraconazole, ritonavir, or Riociguat
• have severely reduced liver function
• have recently had a Stroke or Heart Attack
• have an irregular heartbeat that may be life-threatening
• have unstable Angina caused by Coronary Artery Disease
• have severe low blood pressure (less than 90/50 mmHg) when starting Pms Sildenafil R

There may be an interaction between sildenafil and any of the following:

• alcohol
• Aliskiren
• alpha-agonists (e.g., Clonidine, methyldopa)
• alpha-blockers (e.g., Alfuzosin, doxazosin, Prazosin)
• Alprostadil
• angiotensin converting enzyme inhibitors (ACEIs; Captopril, Enalapril, Ramipril)
• angiotensin receptor blockers (ARBs; e.g., Candesartan, Irbesartan, Losartan)
• Apalutamide
• Aprepitant
• "azole" antifungals (e.g., fluconazole, ketoconazole, itraconazole, Voriconazole)
• beta-adrenergic blockers (e.g., Atenolol, Propranolol, Sotalol)
• Bosentan
• calcium channel blockers (e.g., Amlodipine, Diltiazem, Nifedipine, Verapamil)
• Carbamazepine
• ciprofloxacin
• Cobicistat
• conivaptan
• Deferasirox
• diuretics (water pills; e.g., Furosemide, Hydrochlorothiazide, triamterene)
• Dronedarone
• Enzalutamide
• grapefruit juice
• Guanfacine
• Hepatitis C antivirals (e.g., dasabuvir, ombitasvir, paritaprevir)
• HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., efavirenz, etravirine, nevirapine)
• HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
• Hydralazine
• levodopa
• lumacaftor and Ivacaftor
• macrolide antibiotics (e.g., clarithromycin, erythromycin)
• mifepristone
• Mitotane
• Modafinil
• nitrates (e.g., nitroglycerin, isosorbide mononitrate, isosorbide dinitrate, or amyl nitrite "poppers")
• Phenobarbital
• Phenytoin
• other phosphodiesterase inhibitors (e.g., Tadalafil, Vardenafil)
• Pramipexole
• primidone
• rifabutin
• rifampin
• riociguat
• Selegiline
• St. John's wort
• Sarilumab
• siltuximab
• "statin" anticholesterol medications (e.g., Atorvastatin, Lovastatin, Simvastatin)
• Stiripentol
• Tacrolimus
• Tizanidine
• Tocilizumab
• tyrosine kinase inhibitors (e.g., Dasatinib, imatinib, Nilotinib, Sunitinib)

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Pms Sildenafil R. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Pms Sildenafil R.

Bleeding problems: Sildenafil may cause your body to take longer to stop bleeding. If you have bleeding problems or a bleeding disorder, discuss with your doctor how Pms Sildenafil R may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Blood pressure: Sildenafil can cause a rapid decrease in blood pressure that may add to the blood pressure-lowering effect of other medications. Tell your doctor if you are taking medications to treat high blood pressure. If you are taking medication for high blood pressure, discuss with your doctor how Pms Sildenafil R may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Sildenafil R, and whether any special monitoring is needed.

Grapefruit juice: Grapefruit juice can increase the amount of sildenafil in your blood. Do not drink grapefruit juice while taking this medication.

Heart or blood vessel problems: Sildenafil can make heart or blood vessel problems worse. If you have had a heart attack, stroke, or life-threatening abnormal heart rhythm within the last 6 months, or have angina, chest pain, an irregular heartbeat, or high or low blood pressure, discuss with your doctor how Pms Sildenafil R may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Sildenafil R, and whether any special monitoring is needed.

Liver function: If you have liver problems, discuss with your doctor how Pms Sildenafil R may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Sildenafil R, and whether any special monitoring is needed. People with severely reduced liver function should not use Pms Sildenafil R.

Lung problems: Sildenafil is not recommended for people with a form of high blood pressure in the lungs called pulmonary veno-occlusive disease. If you have pulmonary veno-occlusive disease or experience sudden cough, shortness of breath, chest pain, or rapid breathing, talk to your doctor before taking Pms Sildenafil R.

Nitrate-containing medications: Sildenafil should never be taken with any medications that contain nitrates. Blood pressure may suddenly drop to life-threatening levels if sildenafil is taken with any nitrate-containing medication (e.g., nitroglycerin tablets, spray, or patches) or any other nitrates (e.g., isosorbide dinitrate or amyl nitrite "poppers"). Dizziness, fainting spells, heart attack, or stroke may be experienced.

Penis deformation: Men with an anatomical deformation of the penis such as angulation, cavernosal fibrosis, or Peyronie's disease should be closely monitored by their doctor while taking Pms Sildenafil R.

Prolonged erection: Tell your doctor if you have ever had an erection that lasted longer than 4 hours, or have Sickle Cell Anemia or Leukemia, before taking Pms Sildenafil R.

Prostate problems: Tell your doctor if you are taking medications to treat prostate problems, such as alpha-blockers (e.g., Doxazosin), as sildenafil combined with these medications may cause dangerously low blood pressure.

Vision problems: If you have or have had a temporary decrease or permanent loss of vision in one or both eyes, including a condition called non-arteritic anterior ischemic optic Neuropathy (NAION), or if you have retinitis pigmentosa, tell your doctor before taking Pms Sildenafil R.

Pms Sildenafil R can cause partial or complete vision loss that may be temporary or permanent. If you experience a sudden loss of vision in one or both eyes or other vision-related problems, contact your doctor immediately. If you do experience vision changes, do not drive or operate machinery until your vision returns to normal.

Pregnancy: Pms Sildenafil R should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Pms Sildenafil R, contact your doctor immediately.

Breast-feeding: Pms Sildenafil R may pass into breast milk. If you are a breast-feeding mother and are taking sildenafil, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of this medication have not been established for children with pulmonary hypertension.

<p><a href="/drug/gd-sildenafil">Sildenafil</a> belongs to the family of medications known as <i>phosphodiesterase type 5 inhibitors</i>. It is used to <b>treat pulmonary hypertension</b> (high blood pressure in the blood vessels between the heart and lungs) when people have not responded to conventional treatment.</p><p> It helps reduce pulmonary blood pressure by widening blood vessels.</p><p> <b><a href="/drug/pms-sildenafil">Pms Sildenafil</a> R may be available under multiple brand names and/or in several different forms.</b> Any specific brand name of Pms Sildenafil R may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Pms Sildenafil R may not be used for all of the conditions discussed here.</p><p> <b>Your doctor may have suggested this medication for conditions other than those listed in these drug information articles.</b> If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. <b>Do not stop taking Pms Sildenafil R without consulting your doctor.</b></p><p><b>Do not give this medication to anyone else, even if they have the same symptoms as you do.</b> It can be harmful for people to take this medication if their doctor has not prescribed it. </p>