Propyl Thyracil

The usual adult starting dose of Propyl Thyracil (Propylthiouracil) is 50 mg to 100 mg every 8 hours, with increases as necessary up to a maximum of 500 mg daily or as directed by your doctor. When doses larger than 300 mg per day are needed, the medication should be taken every 4 to 6 hours. Children's doses are based on their body weight.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose or schedule different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Propyl Thyracil (Propylthiouracil) exactly as prescribed by your doctor. Propyl Thyracil (Propylthiouracil) should not be stopped suddenly but should be withdrawn over a period of 1 to 2 months under the direction of your doctor.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Propyl Thyracil (Propylthiouracil) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

In addition to its desired action, this medication may cause some adverse effects, notably: it may cause spots or redness of the skin; it may cause dizziness - use caution when getting up from a lying or sitting position and use caution if driving; it may cause a general feeling of weakness; it may alter your sense of taste; it may cause nausea and vomiting. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.

50 mg
Each white tablet engraved with "PLB" on one side and "PPT" over score "50" on the other contains 50 mg of Propyl Thyracil (Propylthiouracil).

100 mg
Each white, round, biconvex tablet engraved with "PLB" on one side and "PPT" over score "100" on the other contains 100 mg of Propyl Thyracil (Propylthiouracil).

Do not take Propyl Thyracil (Propylthiouracil) if you:

• are allergic to Propyl Thyracil (Propylthiouracil) or any ingredient of the medication
• are breast-feeding

There may be an interaction between Propyl Thyracil (Propylthiouracil) and any of the following:

• bacillus Calmette-Guérin (BCG)
• beta-blockers (e.g., Atenolol, Metoprolol, Propranolol)
• Cladribine
• Clozapine
• Deferiprone
• Digoxin
• medications that contain iodine
• Mesalamine
• theophyllines (e.g., Aminophylline, Oxtriphylline, Theophylline)
• Warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Propyl Thyracil (Propylthiouracil). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Propyl Thyracil (Propylthiouracil).

Blood counts: Propyl Thyracil (Propylthiouracil) can decrease the number of neutrophils (a type of white blood cell that helps fight infection), red blood cells (which carry oxygen), and platelets (which help your blood to clot). If you notice any signs of infection (e.g., fever, chills, or sore throat) or unusual bleeding or bruising, contact your doctor immediately.

Hypothyroidism: Your dose of Propyl Thyracil (Propylthiouracil) will be reduced or temporarily discontinued by your doctor if signs of hypothyroidism (such as weight gain, clumsiness, and intolerance of cold temperatures) occur during treatment.

Inflamed blood vessels: Rarely, Propyl Thyracil (Propylthiouracil) can cause blood vessels to become inflamed. This inflammation can cause changes to the blood vessels, reducing blood flow and possibly causing scarring, weakening, or narrowing of the blood vessels. This can result in organ or tissue damage. If you experience any unexpected side effects, such as difficulty breathing, rash, blood in the urine, or coughing up blood, contact your doctor as soon as possible.

Kidney problems: If you have kidney problems, discuss with your doctor how Propyl Thyracil (Propylthiouracil) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Propyl Thyracil (Propylthiouracil), and whether any special monitoring is needed.

Liver function: Propyl Thyracil (Propylthiouracil) may reduce liver function and can cause liver failure. If you have liver problems, discuss with your doctor how Propyl Thyracil (Propylthiouracil) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Propyl Thyracil (Propylthiouracil), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Propyl Thyracil (Propylthiouracil).

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Size of thyroid gland: Tell your doctor if the size of your thyroid gland increases during treatment with Propyl Thyracil (Propylthiouracil). An enlarged thyroid gland is a sign that you may need a lower dose of the medication.

Pregnancy: Propyl Thyracil (Propylthiouracil) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Propyl Thyracil (Propylthiouracil), contact your doctor immediately. Women who may become pregnant should use effective birth control while taking Propyl Thyracil (Propylthiouracil).

Breast-feeding: Propyl Thyracil (Propylthiouracil) passes into breast milk. If you are breast-feeding and are taking Propyl Thyracil (Propylthiouracil), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

This medication is typically used 3 times a day. However, your pharmacist may have suggested a different schedule that is more appropriate for you. Take it regularly and continuously to maintain its beneficial effects. Important: Follow the instructions on the label. Do not use more of this product, or more often, than prescribed. It is not advisable to stop using this product suddenly, particularly if you have been on it for several weeks. If you are considering stopping the medication, talk to your pharmacist first. You should take this medication at approximately the same time each day. This medication may be taken with or without food.