Exelon Patch 15

The usual recommended starting dose is to apply one patch of the lowest dose (4.6 mg released every 24 hours) once a day. Your doctor may increase the dose after 4 weeks of treatment. The highest dose recommended is 13.3 mg every 24 hours.

Apply the patch to clean, dry, non-irritated skin on a flat body surface such as the chest, upper back, lower back, or upper arm. Make sure there is no hair, powder, oil, moisturizer, or lotion at the application site. Press the patch firmly in place with the palm of the hand for approximately 30 seconds, making sure the contact is complete, especially around the edges.

Each patch may be worn continuously for 24 hours, after which time the old patch should be removed and a new patch should be applied. Apply the new patch on a different skin site after removal of the previous one and do not apply a new patch to the same spot for at least 2 weeks. Consult the package insert, your doctor, or your pharmacist for specific instructions on how to use and properly dispose of the medication.

Only one patch may be worn at a time. After 24 hours, there is still medication remaining in the patch. If two patches are worn at the same time, there is a high likelihood of severe side effects occurring, including Heart Attack and death. Do not use the patch if it is cut, damaged, or altered in any way.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use Exelon Patch 15 (Rivastigmine-transdermal) exactly as prescribed by your doctor. If you forget to apply a new rivastigmine patch, remove the old one and apply a new patch as soon as possible. Continue with your regular dosing schedule for your next patch. Do not apply two patches to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. If you miss more than 3 days of applying the rivastigmine patch, consult your doctor first before you begin to apply the next patch.

Store Exelon Patch 15 (Rivastigmine-transdermal) at room temperature, in the original packaging. Protect it from light and heat, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

In addition to its desired action, this medication may cause some adverse effects, notably: it may decrease your appetite; it may cause diarrhea; it may cause dizziness - use caution when getting up from a lying or sitting position and use caution if driving; it may cause nausea or, rarely, vomiting; occasionally, it may cause weight loss. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.

Exelon Patch 5
Each patch of 5 cm² contains 9 mg of rivastigmine base, with in vivo release rate of 4.6 mg/24 hours. The outside of the backing layer is beige and labelled with "PrEXELON* PATCH 5 (rivastigmine) 4.6 mg/24 h" and "AMCX". Nonmedicinal ingredients: acrylic copolymer, poly (butylmethacrylate, methyl-methacrylate), silicone adhesive applied to a flexible polymer backing film, silicone oil, and vitamin E.

Exelon Patch 10
Each patch of 10 cm² contains 18 mg of rivastigmine base, with in vivo release rate of 9.5 mg/24 hours. The outside of the backing layer is beige and labelled with "PrEXELON* PATCH 10 (rivastigmine) 9.5 mg/24 h" and "BHDI". Nonmedicinal ingredients: acrylic copolymer, poly (butylmethacrylate, methyl-methacrylate), silicone adhesive applied to a flexible polymer backing film, silicone oil, and vitamin E.

Exelon Patch 15
Each patch of 15 cm² contains 27 mg of rivastigmine base, with in vivo release rate of 13.3 mg/24 hours. The outside of the backing layer is beige and labelled with "PrEXELON* PATCH 15 (rivastigmine) 13.3 mg/24 h" and "CNFU". Nonmedicinal ingredients: acrylic copolymer, poly (butylmethacrylate, methyl-methacrylate), silicone adhesive applied to a flexible polymer backing film, silicone oil, and vitamin E.

Do not use rivastigmine patch if you:

• are allergic to rivastigmine or any ingredients of the medication
• are allergic to medications that are similar to rivastigmine
• have had a severe skin reaction when using rivastigmine patches
• have severely reduced liver function

There may be an interaction between rivastigmine and any of the following:

• alcohol
• aclidinium
• Amiodarone
• antihistamines (e.g., brompheniramine, Chlorpheniramine)
• antipsychotic medications (e.g., Aripiprazole, Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine)
• atropine
• azelastine
• belladonna
• Benztropine
• beta-blockers (e.g., Atenolol, Metoprolol, Propranolol)
• Ceritinib
• cholinergic medications (e.g., Bethanechol)
• Clonidine
• corticosteroids (e.g., Dexamethasone, Hydrocortisone, Prednisone)
• Cyclobenzaprine
• Darifenacin
• Digoxin
• Diltiazem
• Dipyridamole
• Disopyramide
• Donepezil
• Dronedarone
• Fingolimod
• Flavoxate
• Galantamine
• glycopyrrolate
• Guanfacine
• ipratropium
• Ivabradine
• ketotifen
• Lacosamide
• Lanreotide
• methyldopa
• Metoclopramide
• Moclobemide
• neuromuscular blocking agents (e.g., atracurium, pancuronium, succinylcholine)
• Octreotide
• orphenadrine
• Oxybutynin
• Pasireotide
• Propafenone
• quinidine
• scopolamine
• succinylcholine
• tiotropium
• Tizanidine
• Tofacitinib
• Tolterodine
• Tranylcypromine
• tricyclic antidepressants (e.g., Amitriptyline, Clomipramine, Desipramine, Trimipramine)
• umeclidinium

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Exelon Patch 15 (Rivastigmine-transdermal). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Exelon Patch 15 (Rivastigmine-transdermal).

Breathing conditions: Rivastigmine may cause breathing problems to worsen. If you have a history of Asthma or obstructive lung disease (e.g., emphysema, chronic Bronchitis), discuss with your doctor how Exelon Patch 15 (Rivastigmine-transdermal) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Exelon Patch 15 (Rivastigmine-transdermal), and whether any special monitoring is needed.

Drowsiness/reduced alertness: Exelon Patch 15 (Rivastigmine-transdermal) may cause dizziness or drowsiness, mainly when starting treatment or increasing the dose. Your doctor will advise you whether it is safe for you to drive vehicles and operate machinery. If you feel dizzy or drowsy, do not drive, use machines, or perform any other tasks that require your attention.

Heart disease: People with certain types of heart disease (e.g., Congestive Heart Failure, Coronary Artery Disease) are more likely to experience symptoms of heart disease as a result of rivastigmine slowing down the heart rate. If you have heart disease, discuss with your doctor how Exelon Patch 15 (Rivastigmine-transdermal) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Exelon Patch 15 (Rivastigmine-transdermal), and whether any special monitoring is needed.

Incorrect use of medication: Rivastigmine patches are intended to be worn one at a time. Forgetting to remove a patch and applying a second one, can lead to severe, sometimes fatal side effects. If you experience nausea, vomiting, diarrhea, hallucinations, high blood pressure, decreased heart rate or falls, when you previously have tolerated the medication well, this may indicate an incorrect use of the patches. Report any unusual side effects to your doctor as soon as possible.

Kidney function: If you have reduced kidney function or Kidney Disease, discuss with your doctor how Exelon Patch 15 (Rivastigmine-transdermal) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Exelon Patch 15 (Rivastigmine-transdermal), and whether any special monitoring is needed.

Liver function: Decreased liver function or liver disease can lead to Exelon Patch 15 (Rivastigmine-transdermal) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Exelon Patch 15 (Rivastigmine-transdermal) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Exelon Patch 15 (Rivastigmine-transdermal), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Exelon Patch 15 (Rivastigmine-transdermal). People with severely reduced liver function should not use Exelon Patch 15 (Rivastigmine-transdermal).

Low body weight: People who weigh less than 50 kg may experience more side effects than people who weigh more than 50 kg. Discuss with your doctor any concerns you may have about using the rivastigmine patch.

Seizures: People who have a history of seizures may experience an increase in seizures when using rivastigmine patch. If you have a history of seizures, discuss with your doctor how Exelon Patch 15 (Rivastigmine-transdermal) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Exelon Patch 15 (Rivastigmine-transdermal), and whether any special monitoring is needed.

Stomach problems: The use of rivastigmine patch is associated with significant stomach side effects including diarrhea, nausea, vomiting, loss of appetite, and weight loss. If these side effects persist or they bother you, speak to your doctor. If you have a history of stomach ulcers or are at risk of developing ulcers, discuss with your doctor how Exelon Patch 15 (Rivastigmine-transdermal) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Exelon Patch 15 (Rivastigmine-transdermal), and whether any special monitoring is needed.

Stopping and restarting treatment: If you miss more than 3 days' worth of treatment, talk to your doctor about how to safely restart the medication.

Surgery: Rivastigmine increases the effects of some medications that are used during surgery. If you are going to have surgery, make sure you let all the doctors, including dentists, know that you are using rivastigmine patch.

Pregnancy: Exelon Patch 15 (Rivastigmine-transdermal) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Exelon Patch 15 (Rivastigmine-transdermal), contact your doctor immediately.

Breast-feeding: It is not known if rivastigmine passes into breast milk. If you are a breast-feeding mother and are taking Exelon Patch 15 (Rivastigmine-transdermal), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Exelon Patch 15 (Rivastigmine-transdermal) have not been established for children.

This medication is contained in a patch that is to be applied to your skin on your front or back, above the waist. Avoid areas where the skin is oily, broken or irritated. If the area is hairy, clip hair with scissors. Do not shave it, it would irritate the area.<br/><br/>Avoid touching the sticky side when handling the patch. Apply the patch on the skin and press firmly. When you change patches, apply the new one at a different location. Wait two weeks before applying a patch at the same location. Patches are waterproof; you may swim or take a shower. If your patch comes off during the day, reapply it or replace it with a new one.<br/><br/>The patch may cause itching or a rash where it has been applied. If such a reaction persists, consult your pharmacist. Heat may increase drug absorption. Avoid heat sources such as heating pads, electric blankets, saunas, heated waterbeds, hot baths or sun bathe. Call your health care professional if you get a fever. This medication is typically used only once a day. However, your pharmacist may have suggested a different schedule that is more appropriate for you. Important: Follow the instructions on the label. Do not use more of this product, or more often, than prescribed. It must be used regularly and continuously to maintain its beneficial effects. Be sure to keep an adequate supply on hand.