
Fxt 40
Fluoxetine
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Fxt 40 - clinical reference
A licensed healthcare practitioner can help you understand what applies to your specific situation.
To treat depression, the recommended starting dose of FXT 40 (Fluoxetine) for adults is 20 mg. After several weeks, your doctor may advise you to increase the dose if your symptoms have not improved. The maximum recommended dose of FXT 40 (Fluoxetine) is 60 mg daily. Once your symptoms have been brought under control, the lowest effective dose of FXT 40 (Fluoxetine) as prescribed by your doctor should be used to keep the symptoms from coming back. Your doctor may advise you to keep taking FXT 40 (Fluoxetine) for several months.
For the eating disorder bulimia nervosa, the recommended adult dosage is 60 mg taken daily, although lower doses may be effective.
The recommended dose of FXT 40 (Fluoxetine) to treat obsessive-compulsive disorder ranges from 20 mg to 60 mg taken once daily.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
FXT 40 (Fluoxetine) is generally taken once daily, in the morning. It may be taken with food or on an empty stomach.
It is important to take FXT 40 (Fluoxetine) exactly as prescribed by your doctor. If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store FXT 40 (Fluoxetine) at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
FXT 40 is no longer being manufactured for sale in Canada. For brands that may still be available, search under "FXT 40 (Fluoxetine)". This article is being kept available for reference purposes only. If you are using FXT 40 (Fluoxetine), speak with your doctor or pharmacist for information about your treatment options.
Do not take FXT 40 (Fluoxetine) if you:
- are allergic to FXT 40 (Fluoxetine) or any ingredients of the medication
- have taken a MAO inhibitor (e.g., Phenelzine, Tranylcypromine) or thioridazine within the past 14 days
Do not take MAO inhibitors or thioridazine until at least 5 weeks after you stop your treatment with FXT 40 (Fluoxetine).
There may be an interaction between FXT 40 (Fluoxetine) and any of the following:
- Abiraterone
- acetylsalicylic acid (Asa)
- alcohol
- Alfuzosin
- amantadine
- Amiodarone
- amphetamines (e.g., Dextroamphetamine, Lisdexamfetamine)
- anti-cancer medications (e.g., Bosentan, Capecitabine, Doxorubicin, Fluorouracil)
- antihistamines (e.g,. cetirizine, doxylamine, Diphenhydramine, Hydroxyzine, Loratadine)
- antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
- Apixaban
- Aprepitant
- Atomoxetine
- azole antifungals (e.g. fluconazole, ketoconazole, Voriconazole)
- barbiturates (e.g., Phenobarbital, secobarbital)
- benzodiazepines (e.g., Alprazolam, Diazepam, Lorazepam)
- beta-adrenergic blockers (e.g., Atenolol, Propranolol, Sotalol)
- beta-2 agonists (e.g., formoterol, Indacaterol, salmeterol)
- Bromocriptine
- Bupropion
- Buspirone
- cabergolinecaptopril
- Celecoxib
- chloral hydrate
- chloroquine
- Cimetidine
- clopidrogrel
- dabigatran
- Degarelix
- Desmopressin
- Dextromethorphan
- diabetes medications (e.g., chlorpropamide, glipizide, Glyburide, insulin, Rosiglitazone)
- Disopyramide
- dofetilide
- Domperidone
- Dronedarone
- Enzalutamide
- Famotidine
- Fingolimod
- Flecainide
- Fluvastatin
- Galantamine
- Gemfibrozil
- Heparin
- HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., delavirdine, efavirenz, etravirine, nevirapine)
- HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
- hydrochlorthiazide
- Irbesartan
- Linezolid
- Leuprolide
- Levothyroxine
- linezolid
- lithium
- Losartan
- low molecular weight heparins (e.g., Dalteparin, Enoxaparin, Nadroparin)
- macrolide antibiotics (e.g., clarithromycin, erythromycin)
- Maprotiline
- Mefloquine
- Methadone
- Metoclopramide
- methylene blue
- Metronidazole
- Mexiletine
- mifepristone
- Mirabegron
- Mirtazapine
- monoamine oxidase inhibitors (M.O.S. e.g., Moclobemide, phenelzine, Rasagiline, Selegiline, tranylcypromine)
- muscle relaxants (e.g., Cyclobenzaprine, methocarbamol, orphenadrine)
- narcotic pain relievers (e.g., Codeine, Fentanyl, Morphine, Oxycodone)
- nefazodone
- Nifedipine
- non-steroidal anti-inflammatory medications (NSAIDs; e.g., Diclofenac, Ibuprofen, Naproxen)
- Octreotide
- Omeprazole
- pentamidine
- Pentoxifylline
- Prasugrel
- procainamide
- Propafenone
- protein kinase inhibitors (e.g., Bosutinib, Dasatinib, imatinib, Nilotinib)
- quinidine
- quinine
- quinolone antibiotics (e.g., ciprofloxacin, Norfloxacin, Ofloxacin)
- rifampin
- Rivaroxaban
- Romidepsin
- St. John's wort
- scopolamine
- seizure medications (e.g., Carbamazepine, Clobazam, Gabapentin, Levetiracetam, Phenytoin, primidone, Topiramate, Valproic acid, zonisamide)
- other selective serotonin reuptake inhibitors (SSRIs; e.g., Citalopram, Duloxetine, FXT 40 (Fluoxetine), Paroxetine, Sertraline)
- serotonin antagonists (e.g., Granisetron, Ondansetron)
- serotonin/norepinephrine reuptake inhibitors (SNRIs; e.g., Desvenlafaxine, duloxetine, Venlafaxine)
- Solifenacin
- sulfadiazine
- sulfamethoxazole
- Tacrolimus
- Tamoxifen
- terbinafine
- Tetrabenazine
- Ticagrelor
- Ticlopidine
- Tolterodine
- Tramadol
- Trazodone
- tricyclic antidepressants (e.g., Amitriptyline, Desipramine, Imipramine, Trimipramine)
- Trimethoprim
- "triptan" migraine medications (e.g., Eletriptan, Sumatriptan)
- Tryptophan
- Vandetanib
- Vemurafenib
- vitamin E
- Warfarin
- Zafirlukast
- Zopiclone
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with FXT 40 (Fluoxetine). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use FXT 40 (Fluoxetine).
Allergy: Approximately 7% of people who take FXT 40 (Fluoxetine) develop a rash or hives. Almost one third of these people need to stop treatment because of the rash. If you get a skin rash while taking FXT 40 (Fluoxetine), consult your doctor as soon as possible.
Bleeding: FXT 40 (Fluoxetine) may cause a reduced number of platelets in the blood, which can make it difficult to stop cuts from bleeding. If you notice any signs of bleeding, such as frequent nosebleeds, unexplained bruising, or black and tarry stools, notify your doctor as soon as possible. Your doctor will order routine blood tests to make sure potential problems are caught early.
Bone Health: FXT 40 (Fluoxetine), like other SSRI medications, may increase the risk of bone fracture, especially if you are a senior or have Osteoporosis or other major risk factors for breaking a bone. Take extra care to avoid falls, especially if you get dizzy or have Low Blood Pressure. Your doctor may monitor your bones while you are taking FXT 40 (Fluoxetine).
Diabetes: FXT 40 (Fluoxetine) may cause changes in blood glucose control. If you have diabetes, discuss with your doctor how FXT 40 (Fluoxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of FXT 40 (Fluoxetine), and whether any special monitoring is needed.
Your doctor may want you to monitor your blood sugar more carefully while you are taking FXT 40 (Fluoxetine).
Drowsiness/reduced alertness: FXT 40 (Fluoxetine) may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid these and other hazardous tasks until you have determined how FXT 40 (Fluoxetine) affects you.
Glaucoma: FXT 40 (Fluoxetine) may cause the symptoms of glaucoma (increased pressure in the eye) to become worse. If you have glaucoma, discuss with your doctor how FXT 40 (Fluoxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of FXT 40 (Fluoxetine), and whether any special monitoring is needed. Report any changes in vision to your doctor as soon as possible while you are taking FXT 40 (Fluoxetine).
Heart rhythm: FXT 40 (Fluoxetine) can cause changes to the normal rhythm of the heart, including an irregular heartbeat called QT prolongation. QT prolongation is a serious life-threatening condition that can cause fainting, seizures, and sudden death. If you are at risk for heart rhythm problems (e.g., people with heart failure, Angina, low potassium or magnesium levels), discuss with your doctor how FXT 40 (Fluoxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of FXT 40 (Fluoxetine), and whether any special monitoring is needed.
Kidney function: Severe Kidney Disease may affect how FXT 40 (Fluoxetine) is removed from the body and contribute to side effects. If you have reduced kidney function or kidney disease, discuss with your doctor how FXT 40 (Fluoxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of FXT 40 (Fluoxetine), and whether any special monitoring is needed.
Liver function: Liver disease or reduced liver function may cause FXT 40 (Fluoxetine) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how FXT 40 (Fluoxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of FXT 40 (Fluoxetine), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking FXT 40 (Fluoxetine).
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Low sodium levels: FXT 40 (Fluoxetine) may cause low sodium levels, especially for seniors, people who are dehydrated, and people taking diuretics (water pills). Contact your doctor if you notice symptoms of low sodium such as confusion, concentration or memory problems, weakness, or unsteadiness.
Psychiatric Conditions: FXT 40 (Fluoxetine) has been reported to cause manic episodes, particularly for people who have bipolar disorder. Signs of mania include extreme levels of energy, hallucinations, suspiciousness, aggression or difficulty focusing your thoughts. If you experience any of these, or if you notice these signs in a family member who is taking FXT 40 (Fluoxetine), contact your doctor immediately. You should be closely monitored by your doctor for emotional and behaviour changes while taking FXT 40 (Fluoxetine).
Seizures: There have been occasional reports of seizures occurring with FXT 40 (Fluoxetine). Seizures are more likely to occur when higher doses of FXT 40 (Fluoxetine) are taken. If you have a history of Epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how FXT 40 (Fluoxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of FXT 40 (Fluoxetine), and whether any special monitoring is needed.
Serotonin Syndrome/ Neuroleptic Malignant Syndrome : Severe reactions are possible when FXT 40 (Fluoxetine) is combined with other medications that act on serotonin, such as tricyclic antidepressants and certain medications for migraine headache. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, changes in mental state including delirium and agitation. Coma and death are possible.
If you are taking other medications, discuss with your doctor how these medications may affect your medical condition, how your medical condition may affect the dosing and effectiveness of these medications, and whether any special monitoring is needed.
Stopping the medication: Some people experience withdrawal effects if FXT 40 (Fluoxetine) is suddenly stopped. Withdrawal symptoms may include headache, difficulty sleeping, numbness, tingling burning or prickling sensations, nervousness, anxiety, nausea, sweating or weakness. Before stopping the medication, talk to your doctor.
Suicidal or agitated behaviour: People taking FXT 40 (Fluoxetine) may feel agitated (restless, anxious, aggressive, emotional, and feeling not like themselves), or they may want to hurt themselves or others. If you experience these side effects or notice them in a family member who is taking FXT 40 (Fluoxetine), contact your doctor immediately. You should be closely monitored by your doctor for emotional and behaviour changes while taking FXT 40 (Fluoxetine).
Pregnancy: It has been reported that babies born to women who took similar medications during the last trimester of their pregnancy may experience adverse effects (such as breathing problems, seizures, trouble feeding, jitteriness, irritability, and constant crying). There may also be a slight increase in the risk of birth defects if FXT 40 (Fluoxetine) is taken early during the pregnancy. FXT 40 (Fluoxetine) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking FXT 40 (Fluoxetine), contact your doctor immediately. Some babies whose mothers took FXT 40 (Fluoxetine) during pregnancy have had withdrawal effects.
Breast-feeding: FXT 40 (Fluoxetine) passes into breast milk. If you are a breast-feeding mother and are taking FXT 40 (Fluoxetine), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using FXT 40 (Fluoxetine) have not been established for children. The use of FXT 40 (Fluoxetine) by children and adolescents may cause behavioural and emotional changes, such as suicidal thoughts and behaviour.









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