Teva Bupropion Xl

The recommended starting dose of bupropion extended-release tablets for treatment of major depressive disorder is 150 mg daily, taken in the morning. This dose may be increased to 300 mg daily after 1 week at the lower dose.

For prevention of seasonal depression, Teva Bupropion Xl should be started in the autumn before symptoms of depression develop and continued through the winter. The usual starting dose is 150 mg taken once daily in the morning. It may be increased to 300 mg taken once daily after 1 week at the lower dose. For people taking 300 mg daily, the dose should be reduced to 150 mg daily for 2 weeks prior to stopping Teva Bupropion Xl in the spring.

Bupropion extended-release tablets should be swallowed whole with fluids. They should not be chewed, crushed, or halved, as this may affect how Teva Bupropion Xl is absorbed by the body and result in unwanted side effects.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Teva Bupropion Xl exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Teva Bupropion Xl at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

In addition to its desired action, this medication may cause some adverse effects, notably: it may cause dryness of the mouth; it may cause headaches; it may cause constipation - to prevent this, drink plenty of water or juice, and eat more dietary fibre; it may cause dizziness - use caution when getting up from a lying or sitting position and use caution if driving; it may cause sleep disturbances or insomnia; it may cause nausea or, rarely, vomiting. Each person may react differently to a treatment. If you think this medication may be causing adverse effects (including those described here, or others), talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem.

150 mg
Each white-to-off-white, round, biconvex, film-coated tablet, with a black imprint "WPI" and "3331" on one side and plain on the other side, contains 150 mg of bupropion. Nonmedicinal ingredients: hydroxypropyl cellulose, silicified microcrystalline cellulose, stearic acid; film coating: ethylcellulose, hydroxypropyl cellulose, methacrylic acid copolymer, talc, titanium dioxide, triethyl citrate; imprinting ink: hypromellose, iron oxide black, isopropyl alcohol, and propylene glycol.

300 mg
Each white-to-off-white, round, biconvex, film-coated tablet, with a black imprint "WPI" and "3332" on one side and plain on the other side, contains 300 mg of bupropion. Nonmedicinal ingredients: hydroxypropyl cellulose, silicified microcrystalline cellulose, stearic acid; film coating: ethylcellulose, hydroxypropyl cellulose, methacrylic acid copolymer, talc, titanium dioxide, triethyl citrate; imprinting ink: hypromellose, iron oxide black, isopropyl alcohol, and propylene glycol.

Do not take Teva Bupropion Xl if you:

• are allergic to bupropion or to any of the ingredients of the medication
• are having abrupt withdrawal issues from alcohol, benzodiazepines (e.g., Diazepam, Clonazepam, Lorazepam) or other sedatives (e.g., Phenobarbital)
• are taking another medication that contains bupropion (e.g., Zyban® or Wellbutrin® SR)
• have a seizure disorder or a history of seizures
• have or have had an eating disorder (bulimia or anorexia nervosa)
• have taken a monoamine oxidase inhibitor (MAOI; e.g., Phenelzine, Tranylcypromine) within the last 14 days
• have taken thioridazine (an antipsychotic medication) within the last 14 days

There may be an interaction between bupropion extended-release tablets and any of the following:

• alcohol
• amphetamines (e.g., amphetamine, Dextroamphetamine, Lisdexamfetamine)
• antihistamines (e.g., doxylamine, Diphenhydramine, Hydroxyzine)
• anti-malarial medications (e.g., chloroquine, Mefloquine, Primaquine)
• anti-Parkinson medications (e.g., amantadine, Apomorphine, Bromocriptine, levodopa, Pramipexole, Ropinirole) – dopamine agonists
• antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Risperidone)
• Atomoxetine
• beta-blockers (e.g., Metoprolol, Propranolol, Timolol)
• caffeine
• Carbamazepine
• Clopidogrel
• codeine
• Cyclophosphamide
• Dabrafenib
• dexmethylphenidate
• Dextromethorphan
• Digoxin
• Doxorubicin
• Duloxetine
• efavirenz
• Eliglustat
• Fesoterodine
• Flecainide
• Galantamine
• Gefitinib
• Hydrocodone
• Linezolid
• lithium
• lumacaftor and Ivacaftor
• Meperidine
• Methylphenidate
• Metoclopramide
• Mexiletine
• mifepristone
• Mirtazapine
• monoamine oxidase inhibitors (MAOI; e.g., phenelzine, tranylcypromine, Moclobemide, Rasagiline, Selegiline) – bupropion should not be started until at least 14 days after MAO inhibitors are stopped
• nelfinavir
• Nicotine replacement therapy (e.g., nicotine patch)
• phenobarbital
• Phenytoin
• primidone
• promethazine
• Propafenone
• rifampin
• ritonavir
• selective serotonin reuptake inhibitors (SSRIs; e.g., Citalopram, Escitalopram, Fluoxetine, Paroxetine, Sertraline)
• Tamoxifen
• Tamsulosin
• Tetrabenazine
• theophylline
• Ticlopidine
• Tolterodine
• Tramadol
• tricyclic antidepressants (e.g., Nortriptyline, Imipramine, Desipramine)
• Venlafaxine
• Vilazodone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Teva Bupropion Xl. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Teva Bupropion Xl.

Drowsiness/reduced alertness: Bupropion may affect the mental or physical abilities needed to drive or operate machinery. Avoid driving, operating machinery, or performing other hazardous tasks until you have determined how Teva Bupropion Xl affects you.

Glaucoma: Teva Bupropion Xl may cause the symptoms of glaucoma (increased pressure in the eye) to become worse. If you have glaucoma, discuss with your doctor how Teva Bupropion Xl may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Bupropion Xl, and whether any special monitoring is needed. Report any changes in vision to your doctor as soon as possible while you are taking Teva Bupropion Xl.

Heart disease: It is not known whether bupropion is safe for use by people with a recent history of Heart Attack or unstable heart disease. Bupropion may cause increases in blood pressure. If you have heart problems, discuss with your doctor how Teva Bupropion Xl may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Bupropion Xl, and whether any special monitoring is needed.

Identical medications: Wellbutrin® XL, Wellbutrin® SR, Zyban®, and several other medications contain the same active ingredient (bupropion). If you are taking one of these medications, do not take the other or any other product containing bupropion, as the risk of seizures increases with an increased dosage. To reduce the risk of seizures, the total daily dose of Teva Bupropion Xl should not be greater than 300 mg.

Kidney function: Bupropion is removed from the body by the kidneys. Decreased kidney function can cause Teva Bupropion Xl to build up in the body, causing side effects. If you have Kidney Disease, discuss with your doctor how Teva Bupropion Xl may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Bupropion Xl, and whether any special monitoring is needed.

Liver function: Bupropion is removed from the body by the liver. Decreased liver function can cause Teva Bupropion Xl to build up in the body, causing side effects. If you have liver disease, discuss with your doctor how Teva Bupropion Xl may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Bupropion Xl, and whether any special monitoring is needed.

Teva Bupropion Xl may also cause a decrease in liver function. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Seizure risk: Teva Bupropion Xl may increase the risk of seizures. If you are at risk of seizures, discuss with your doctor how Teva Bupropion Xl may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Bupropion Xl, and whether any special monitoring is needed.

Things which increase the risk of seizures include:

• addiction to cocaine, stimulants (e.g., amphetamines), or opiates (e.g., Morphine, Codeine, Oxycodone)
• Diabetes treated with oral medications or insulin
• excessive alcohol use
• history of head trauma or seizures (including Epilepsy)
• severe liver problems
• tumours of the brain or spinal cord
• use of other medications that make seizures more likely (e.g., antipsychotics, antidepressants, lithium, Theophylline, steroids)
• use of over-the-counter stimulants or appetite suppressants

Stopping the medication: Stopping Teva Bupropion Xl suddenly may lead to side effects. If you are thinking of stopping the medication, check with your doctor first.

Serotonin syndrome: Severe reactions are possible when bupropion is combined with other medications that act on serotonin, such as tricyclic antidepressants and serotonin reuptake inhibitors, other medications used to treat depression. Similar effects occur when too much bupropion is taken or is allowed to build up in the body. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, and changes in mental state including delirium and agitation. These reactions should be treated as a medical emergency and immediate medical treatment should be obtained as coma and death are possible.

Suicidal or agitated behaviour, or other behaviour changes: Especially in the first few weeks or when doses are changed, a small number of people may feel worse instead of better when taking Teva Bupropion Xl. People may feel agitated (restless, anxious, aggressive, emotional, and feeling not like themselves), or they may want to hurt themselves or others. If you experience these side effects or notice them in a family member who is taking Teva Bupropion Xl, contact your doctor immediately. Your doctor will monitor you closely for these side effects while you are taking Teva Bupropion Xl.

Pregnancy: Teva Bupropion Xl should not be taken during pregnancy unless the benefits outweigh the risks. It has been reported that babies born to pregnant women who have taken medications of this kind during pregnancy may be adversely affected. If you become pregnant while taking Teva Bupropion Xl, contact your doctor immediately.

Breast-feeding: Bupropion passes into breast milk. Because Teva Bupropion Xl presents risks to breast-feeding infants, a decision should be made whether to discontinue breast-feeding or to discontinue bupropion, taking into account the importance of the medication to the mother. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using bupropion have not been established for children and adolescents under 18 years of age. The use of Teva Bupropion Xl in children under 18 may cause behavioural and emotional changes, such as suicidal thoughts and behaviour.

Seniors: Because Teva Bupropion Xl is removed from the body by the kidneys and liver, seniors may be at an increased risk of side effects, including seizures, if they use Teva Bupropion Xl. If you are over 65, discuss with your doctor whether any special monitoring is required.

<p><a href="/drug/bupropion-sr">Bupropion</a> belongs to the family of medications known as <i>antidepressants.</i> It is used to <b>treat major Depression and to prevent autumn-winter seasonal depression.</b> It is believed to work by affecting the balance of noradrenaline and dopamine, chemicals that occur naturally in the brain and affect mood.</p><p>For the treatment of depression, the full effects of the medication may not be seen until after several weeks of treatment.</p><p><b>Teva Bupropion Xl may be available under multiple brand names and/or in several different forms.</b> Any specific brand name of Teva Bupropion Xl may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Teva Bupropion Xl may not be used for all of the conditions discussed here.</p><p><b>Your doctor may have suggested Teva Bupropion Xl for conditions other than those listed in these drug information articles.</b> If you have not discussed this with your doctor or are not sure why you are taking Teva Bupropion Xl, speak to your doctor. <b>Do not stop taking Teva Bupropion Xl without consulting your doctor.</b></p><p><b>Do not give Teva Bupropion Xl to anyone else, even if they have the same symptoms as you do.</b> It can be harmful for people to take Teva Bupropion Xl if their doctor has not prescribed it.</p>